Recombinant Human SIGLEC1 protein, His-tagged

• Cat.No.: SIGLEC1-5677H
• Product Overview: Recombinant Human SIGLEC1 aa. (Pro1272~Leu1411 (Accession # Q9BZZ2)) fused with N-terminal His tag was produced in E. coli cells.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: Pro1272~Leu1411
• Description: This gene encodes a member of the immunoglobulin superfamily. The encoded protein is a lectin-like adhesion molecule that binds glycoconjugate ligands on cell surfaces in a sialic acid-dependent manner. It is a type I transmembrane protein expressed only by a subpopulation of macrophages and is involved in mediating cell-cell interactions. Alternative splicing produces a transcript variant encoding an isoform that is soluble rather than membrane-bound; however, the full-length nature of this variant has not been determined.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 16.2kDa
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: >95%
• Characteristic: The isoelectric point is 6.9.
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% sucrose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.

Gene Information

• Gene Name: SIGLEC1 sialic acid binding Ig like lectin 1 [ Homo sapiens (human) ]
• Official Symbol: SIGLEC1
• Synonyms: SIGLEC1; sialic acid binding Ig like lectin 1; SN; CD169; SIGLEC-1; dJ1009E24.1; sialoadhesin; sialic acid binding Ig-like lectin 1, sialoadhesin; sialic acid-binding immunoglobulin-like lectin 1
• Gene ID: 6614
• mRNA Refseq: NM_023068.3
• Protein Refseq: NP_075556.1
• UniProt ID: Q9BZZ2