• Official Full Name

    signal-regulatory protein gamma

  • Overview

    The protein encoded by this gene is a member of the signal-regulatory protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. Alternatively spliced transcript variants encoding different isoforms have been described.
  • Synonyms

    SIRPG; signal-regulatory protein gamma; signal regulatory protein beta 2 , SIRPB2; bA77C3.1; CD172g; SIRP B2; SIRPgamma; CD172 antigen like family member B; CD172 antigen-like family member B; CD172g antigen; FLJ42230; RP11-77C3.2; Signal regulatory protein beta 2; Signal regulatory protein gamma; Signal-regulatory protein beta-2; SIRP beta 2; SIRP gamma; SIRP-b2; SIRP-beta-2; SIRP-gamma; SIRPB2; SIRPG_HUMAN; OTTHUMP00000029998; OTTHUMP00000029999; OTTHUMP00000030000; OTTHUMP00000185041; signal-regulatory protein beta 2; CD172 antigen-like family membe;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Cynomolgus
  • Cynomolgus Monkey
  • Human
  • E.coli
  • HEK293
  • Human Cell
  • Insect cell
  • Mammalian cells
  • Yeast
  • C
  • Fc
  • hFc
  • His
  • Avi
  • GST
  • hIgG
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SIRPG-254H Recombinant Human SIRPG, His-tagged E.coli His 29-360aa
Human SIRPG-2679H Recombinant Human SIRPG, GST-tagged E.coli GST N-term-143aa,C-26aa
Human SIRPG-3787H Active Recombinant Human SIRPG protein(Met1-Ser364), His-tagged HEK293 C-His Met1-Ser364
Human SIRPG-398H Recombinant Human SIRPG Protein, Fc-tagged HEK293 Fc
Human SIRPG-2071HCL Recombinant Human SIRPG cell lysate Human Cell N/A
Human SIRPG-918H Recombinant Human SIRPG protein, His-Avi-tagged HEK293 His-Avi Glu29-Pro360
Human SIRPG-4972H Recombinant Human SIRPG Protein (Met1-Ser364), C-His tagged Mammalian cells C-His Met1-Ser364
Human SIRPG-399H Recombinant Human SIRPG protein (Met1-Ser364), hFc-tagged HEK293 hFc
Human SIRPG-2076H Recombinant Human SIRPG Protein (29-360 aa), His-tagged Yeast His 29-360 aa
Human SIRPG-3495H Recombinant Human SIRPG protein, His-tagged E.coli His 29-360aa
Human SIRPG-09H Active Recombinant Human SIRPG Protein, hIgG/His-tagged Insect cell hIgG/His 29-360aa
Human SIRPG-117H Recombinant Human SIRPG Protein, C-His-tagged E.coli C-His
Human SIRPG-0728H Active Recombinant Human SIRPG protein, Fc-tagged HEK293 Fc Glu29-Ser364
Human SIRPG-447H Recombinant Human SIRPG Protein, Fc-tagged HEK293 Fc 387
Human SIRPG-232H Recombinant Human SIRPG Protein, Glu29-Pro360, C-His-Avi tagged, Biotinylated HEK293 C-His-Avi Glu29-Pro360
Human SIRPG-0727H Active Recombinant Human SIRPG protein, His-Avi-tagged, Biotinylated HEK293 His-Avi Glu29-Ser364
Human SIRPG-5972H Recombinant Human SIRPG Protein (Glu29-Pro360), C-Fc tagged Mammalian cells C-Fc Glu29-Pro360
Cynomolgus SIRPG-1149C Recombinant Cynomolgus SIRPG protein(Met1-His360), His-tagged HEK293 C-His Met1-His360
Cynomolgus SIRPG-1295C Recombinant Cynomolgus SIRPG protein(Met1-His360), hFc-tagged HEK293 C-hFc Met1-His360
Cynomolgus Monkey SIRPG-116C Recombinant Cynomolgus SIRPG, Fc tagged Human Cell His
Cynomolgus Monkey SIRPG-117C Recombinant Cynomolgus SIRPG, His tagged Human Cell GST
Cynomolgus Monkey SIRPG-1002CCL Recombinant Cynomolgus SIRPG cell lysate Human Cell N/A
Cynomolgus Monkey SIRPG-1079CCL Recombinant Cynomolgus SIRPG cell lysate Human Cell N/A
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

SIRPG involved in several pathways and played different roles in them. We selected most pathways SIRPG participated on our site, such as Osteoclast differentiation, which may be useful for your reference. Also, other proteins which involved in the same pathway with SIRPG were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Osteoclast differentiationCSF1R;FCGR3;RELA;TEC;TNFRSF11B;FCGR3B;TREM2;NFKB2;IL1R1

SIRPG has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SIRPG itself. We selected most functions SIRPG had, and list some proteins which have the same functions with SIRPG. You can find most of the proteins on our site.

Function Related Protein
protein bindingCBX5;ATP2A1;RPS10;BCL10;USP25;GRIP1;BEX1;CPT1C;ZKSCAN17

SIRPG has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SIRPG here. Most of them are supplied by our site. Hope this information will be useful for your research of SIRPG.


Research Area

Related articles

Sosale, NG; Rouhiparkouhi, T; et al. Cell rigidity and shape override CD47's "sell"-signaling in phagocytosis by hyperactivating myosin-II. BLOOD 125:542-552(2015).
Nettleship, JE; Ren, JS; et al. Crystal structure of signal regulatory protein gamma (SIRP gamma) in complex with an antibody Fab fragment. BMC STRUCTURAL BIOLOGY 13:-(2013).
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