Recombinant Human SIRPG Protein, Fc-tagged

• Cat.No.: SIRPG-398H
• Product Overview: Recombinant Human SIRPG, transcript variant 1, fused with Fc tag at C-terminal was expressed in HEK293 cells.

Specification

• Description: The protein encoded by this gene is a member of the signal-regulatory protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. Alternatively spliced transcript variants encoding different isoforms have been described.
• Source: HEK293 cells
• Species: Human
• Tag: Fc
• Form: Lyophilized from a 0.2 µM filtered solution ofPBS, pH 7.4
• Molecular Mass: 63.9kD
• AA Sequence: GEEELQMIQPEKLLLVTVGKTATLH CTVTSLLPVGPVLWFRGVGPGRELI YNQKEGHFPRVTTVSDLTKRNNMDF SIRISSITPADVGTYYCVKFRKGSP ENVEFKSGPGTEMALGAKPSAPVVL GPAARTTPEHTVSFTCESHGFSPRD ITLKWFKNGNELSDFQTNVDPTGQS VAYSIRSTARVVLDPWDVRSQVICE VAHVTLQGDPLRGTANLSEAIRVPP TLEVTQQPMRVGNQVNVTCQVRKFY PQSLQLTWSENGNVCQRETASTLTE NKDGTYNWTSWFLVNISDQRDDVVL TCQVKHDGQLAVSKRLALEVTVHQK DQSSDATPVDDIEGRMDEPKSCDKT HTCPPCPAPELLGGPSVFLFPPKPK DTLMISRTPEVTCVVVDVSHEDPEV KFNWYVDGVEVHNAKTKPREEQYNS TYRVVSVLTVLHQDWLNGKEYKCKV SNKALPAPIEKTISKAKGQPREPQV YTLPPSREEMTKNQVSLTCLVKGFY PSDIAVEWESNGQPENNYKTTPPVL DSDGSFFLYSKLTVDKSRWQQGNVF SCSVMHEALHNHYTQKSLSLSPGK
• Endotoxin: Endotoxin level is <0.1 ng/µg of protein (<1EU/µg).
• Purity: >95% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 µg/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Gene Information

• Gene Name: SIRPG signal-regulatory protein gamma [ Homo sapiens ]
• Official Symbol: SIRPG
• Synonyms: SIRPG; signal-regulatory protein gamma; signal regulatory protein beta 2 , SIRPB2; bA77C3.1; CD172g; SIRP B2; SIRPgamma; SIRP-gamma; SIRP beta 2; SIRP-beta-2; CD172g antigen; signal-regulatory protein beta 2; signal-regulatory protein beta-2; CD172 antigen-like family member B; SIRPB2; SIRP-B2; FLJ42230
• Gene ID: 55423
• mRNA Refseq: NM_001039508
• Protein Refseq: NP_001034597
• MIM: 605466
• UniProt ID: Q9P1W8