Recombinant Human SIRPG protein, His-Avi-tagged

• Cat.No.: SIRPG-918H
• Product Overview: Human SIRP gamma Protein is expressed from mammalian with His Tag and Avi Tag at the C-terminal. It contains Glu29-Pro360.

Specification

• Description: Signal regulatory protein gamma (SIRP gamma, designated CD172g), also called SIRP beta 2, is a monomeric 45-47 kDa type I transmembrane protein belonging to the SIRP/SHPS (CD172) family of the Ig superfamily.SIRP gamma is probable immunoglobulin-like cell surface receptor. On binding with CD47, mediates cell-cell adhesion. Engagement on T-cells by CD47 on antigenpresenting cells results in enhanced antigen-specific T-cell proliferation and costimulates T-cell activation.
• Source: HEK293
• Species: Human
• Tag: His-Avi
• Form: Supplied as 0.22um filtered solution in PBS (pH 7.4).
• Molecular Mass: The protein has a predicted MW of 39.7 KDa. Due to glycosylation, the protein migrates to 47- 49KDa based on Bis-Tris PAGE result.
• Protein length: Glu29-Pro360
• Endotoxin: Less than 0.1EU per ug by the LAL method.
• Purity: > 95% as determined by SDS-PAGE; > 95% as determined by HPLC
• Storage: The product should be stored at -70°C. Please do not repeated freeze-thaw cycles.

Gene Information

• Gene Name: SIRPG signal regulatory protein gamma[Homo sapiens (human)]
• Official Symbol: SIRPG
• Synonyms: CD172g antigen; CD172g; FLJ42230; signal-regulatory protein beta 2; Signal-regulatory protein beta-2; signal-regulatory protein gamma; SIRP beta 2; SIRP gamma; SIRP-B2; SIRPB2CD172 antigen-like family member B; SIRP-beta-2; SIRPG; SIRPgamma; SIRP-gammabA77C3.
• Gene ID: 55423
• mRNA Refseq: NM_001039508.2
• Protein Refseq: NP_001034597.1
• MIM: 605466
• UniProt ID: Q9P1W8