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SMYD3

  • Official Full Name

    SET and MYND domain containing 3

  • Synonyms

    SMYD3; SET and MYND domain containing 3; zinc finger, MYND domain containing 1, ZMYND1, ZNFN3A1; SET and MYND domain-containing protein 3; KMT3E; bA74P14.1 (novel protein); zinc finger, MYND domain containing 1; zinc finger MYND domain-containing protein 1; zinc finger protein, subfamily 3A (MYND domain containing), 1; ZMYND1; ZNFN3A1; bA74P14.1; FLJ21080; MGC104324;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Assay Kits
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • E. coli
  • E.coli
  • HEK293
  • HEK293T
  • Human Cell
  • Insect Cell
  • Mammalian Cell
  • Sf9 Insect Cell
  • GST
  • His
  • His (Fc)
  • Avi
  • Flag
  • SUMO
  • Myc
  • DDK
  • Myc|DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SMYD3-263H Recombinant Human SMYD3 protein, GST-tagged E.coli GST
Human SMYD3-1634H Recombinant Human SET And MYND Domain Containing 3, GST-tagged Sf9 Insect Cell GST
Human SMYD3-312H Recombinant Human SMYD3 protein, His&FLAG-tagged HEK293 His/Flag Met1-Ser428
Human SMYD3-666H Recombinant Human SET And MYND Domain Containing 3, His-tagged Human Cell His
Human SMYD3-920H Recombinant Human SMYD3, GST tagged Insect Cell GST
Human SMYD3-698HCL Recombinant Human SMYD3 cell lysate Insect Cell N/A
Human SMYD3-2506HCL Recombinant Human SMYD3 cell lysate Human Cell N/A
Human SMYD3-3102H Recombinant Human SMYD3 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human SMYD3-050H Recombinant Human SMYD3 Protein, His/SUMO-tagged E. coli His/SUMO
Human SMYD3-2062H Recombinant Human SMYD3 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human SMYD3-024H Recombinant Human SMYD3 Protein, His/SUMO-tagged E.coli His/SUMO 35-428
Mouse SMYD3-15657M Recombinant Mouse SMYD3 Protein Mammalian Cell His
Mouse SMYD3-8508M Recombinant Mouse SMYD3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Smyd3-5987M Recombinant Mouse Smyd3 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse SMYD3-8508M-B Recombinant Mouse SMYD3 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque SMYD3-4354R Recombinant Rhesus monkey SMYD3 Protein, His-tagged Mammalian Cell His
Rhesus Macaque SMYD3-4170R Recombinant Rhesus Macaque SMYD3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque SMYD3-4170R-B Recombinant Rhesus Macaque SMYD3 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish SMYD3-3525Z Recombinant Zebrafish SMYD3 Mammalian Cell His
Kit-1868 SMYD3 Homogeneous Assay Kit N/A
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • SMYD3 Related Articles

SMYD3 involved in several pathways and played different roles in them. We selected most pathways SMYD3 participated on our site, such as Chromatin modifying enzymes, Chromatin organization, PKMTs methylate histone lysines, which may be useful for your reference. Also, other proteins which involved in the same pathway with SMYD3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Chromatin modifying enzymesCARM1;MBIP;SUDS3;C20orf20;TADA2A;DR1;BRPF1;TADA1;PADI3
Chromatin organizationATXN7;C3orf75;ELP4;EPC1;CSRP2BP;SMYD2;CARM1;SMYD3;AEBP2
PKMTs methylate histone lysinesSETD3;DPY30;ATF7IP;SMYD2;SUZ12A;EED;EHMT2;AEBP2;PRDM16

SMYD3 has several biochemical functions, for example, RNA polymerase II core binding, RNA polymerase II core promoter sequence-specific DNA binding, RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SMYD3 itself. We selected most functions SMYD3 had, and list some proteins which have the same functions with SMYD3. You can find most of the proteins on our site.

Function Related Protein
RNA polymerase II core bindingZNF326;WAC;KIAA1967;SMYD2;RPRD1B;AGO1;SMYD3;CTR9;CDC73
RNA polymerase II core promoter sequence-specific DNA bindingTFAP2B;SPI1;PAX6;H2AFZ;H3F3A;HNF4A;MITF;SOX8;RUVBL2
RNA polymerase II intronic transcription regulatory region sequence-specific DNA bindingZC3H8;ZNF350;NCOA2;HSF1;HSF2;SMYD3;VAX2;VAX1
histone-lysine N-methyltransferase activityEZH2;WHSC1L1;SUV420H1;SUV39H1B;SETDB1;EHMT1;PRDM9;EHMT1B;SETD7
metal ion bindingPRDM10;ERMP1;ADCY1;RNF34B;SCRT2;CABP1;FTR50;ZNF43;PLAG1

SMYD3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SMYD3 here. Most of them are supplied by our site. Hope this information will be useful for your research of SMYD3.

DDOST; MEST; FAR1; NDUFAB1; NFYB; PBX2; CAMK2B; ZNF57; H3F3C; VANGL1; TRIT1; CYP39A1; q9wmx2-pro_0000037551; polg_hcvh; CDC37

Xu, GL; Liu, GL; et al. The Histone Methyltransferase Smyd2 Is a Negative Regulator of Macrophage Activation by Suppressing Interleukin 6 (IL-6) and Tumor Necrosis Factor alpha (TNF-alpha) Production. JOURNAL OF BIOLOGICAL CHEMISTRY 290:5414-5423(2015).
Spellmon, N; Holcomb, J; et al. Structure and Function of SET and MYND Domain-Containing Proteins. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 16:1406-1428(2015).
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