Recombinant Human SET And MYND Domain Containing 3, GST-tagged

• Cat.No.: SMYD3-1634H
• Product Overview: Recombinant full-length human SMYD3 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

Specification

• Species: Human
• Source: Sf9 Cells
• Tag: GST
• Description: SMYD3 (SET and MYND domain containing 3) is a histone methyltransferase that plays a role in transcriptional regulation as a member of an RNA polymerase complex. The introduction of SMYD3 enhanced cell growth and the histone methyltransferase activity of SMYD3 involved in the proliferation of cancer cells. A variable number of tandems repeat polymorphism in an E2F-1 binding element in the 5-prime flanking region of SMYD3 is a risk factor for human cancers.
• Applications: Western Blot
• Molecular Weight: 71 kDa
• Expression System: Sf9 insect cells using baculovirus
• Form: Recombinant protein stored in 50 mM Tris-HCL, pH 7.5, 150 mM NaCl, 0.1 mM PMSF, 0.25 mM DTT, 10 mM gluthione, 0.1 mM EDTA, 25 % glycerol.
• Purity: > 90 %
• Concentration: 0.1 ug/ul
• Sequences: Full-length
• Storage: Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Gene Information

• Gene Name: SMYD3 SET and MYND domain containing 3 [ Homo sapiens ]
• Official Symbol: SMYD3
• Synonyms: SMYD3; SET and MYND domain containing 3; KMT3E; ZMYND1; ZNFN3A1; FLJ21080; MGC104324; bA74P14.1; bA74P14.1 (novel protein); zinc finger, MYND domain containing 1; zinc finger protein, subfamily 3A (MYND domain containing), 1; EC 2.1.1.43; Zinc finger MYND domain-containing protein 1
• Gene ID: 64754
• mRNA Refseq: NM_001167740
• Protein Refseq: NP_001161212
• MIM: 608783
• UniProt ID: Q9H7B4
• Chromosome Location: 1q44
• Function: histone-lysine N-methyltransferase activity; metal ion binding; methyltransferase activity; protein binding; transferase activity; zinc ion binding