SNX1

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SNX1

Official Full Name sorting nexin 1
Background This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This endosomal protein regulates the cell-surface expression of epidermal growth factor receptor. This protein also has a role in sorting protease-activated receptor-1 from early endosomes to lysosomes. This protein may form oligomeric complexes with family members. This gene results in three transcript variants encoding distinct isoforms.
Synonyms SNX1; sorting nexin 1; sorting nexin-1; HsT17379; MGC8664; SNX1A; Vps5; sorting nexin 1A
    • Species :
    • Cynomolgus Monkey
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Source :
    • E. coli
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Tag :
    • GST
    • His
    • Myc/DDK
    • N/A
    • T7
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human SNX1-3623H Recombinant Human SNX1 protein, GST-tagged E.coli GST
    Human SNX1-800H Recombinant Human SNX1 protein, His-tagged E. coli His
    Human SNX1-1605HCL Recombinant Human SNX1 293 Cell Lysate HEK293 N/A
    Human SNX1-2309H Recombinant Human SNX1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human SNX1-2800H Recombinant Human Sorting Nexin 1, His-tagged E.coli His
    Human SNX1-2991H Recombinant Human Sorting Nexin 1, T7-tagged E.coli T7
    Human SNX1-30609TH Recombinant Human SNX1, His-tagged E.coli His
    Human SNX1-30610TH Recombinant Human SNX1, T7 -tagged E.coli T7
    Mouse Snx1-6019M Recombinant Mouse Snx1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Rat SNX1-5652R Recombinant Rat SNX1 Protein Mammalian Cell His
    Cynomolgus Monkey SNX1-953C Recombinant Cynomolgus SNX1 Protein, His-tagged Mammalian Cell His
    Rhesus Macaque SNX1-4386R Recombinant Rhesus monkey SNX1 Protein, His-tagged Mammalian Cell His

    SNX1 involved in several pathways and played different roles in them. We selected most pathways SNX1 participated on our site, such as Endocytosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with SNX1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Endocytosis PRKCZ; KIF5C; ARPC1A; ARRB2B; STAM2; CAPZA1B; VPS37C; WASLA; VPS25; CAPZB

    SNX1 has several biochemical functions, for example, epidermal growth factor receptor binding, identical protein binding, insulin receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SNX1 itself. We selected most functions SNX1 had, and list some proteins which have the same functions with SNX1. You can find most of the proteins on our site.

    Function Related Protein
    epidermal growth factor receptor binding LINGO1; CBLC; ATXN2; YES1; GRB2; TGFA; AGR2; FAM83B; EFEMP1; RNF126
    identical protein binding IIGP1; ATL3; STAT2; G6PD; KCTD17; SOX10; MUL1A; Serpina1c; TNN; ETNPPL
    insulin receptor binding DOK7; FRS2B; INS1; DOK1B; LMBRD1; DOK6; SLC2A2; GRB10; IGF1; SNX2
    leptin receptor binding SNX2; SNX1; SNX4
    phosphatidylinositol binding ZCCHC2; PXK; MITD1; SNX10B; SNX1A; NOXO1A; SH3PXD2A; SNX32; WDR35; SNX17
    protein binding PAN3; SCARA3; VPS54; C10orf119; LYL1; ABCE1; CREBBP; NR0B1; DNAJB6; MRPL1
    protein heterodimerization activity H2AFJ; PAFAH1B3; LIFR; SUPT4H1; BIK; TAF9; ZHX2; TYRO3; HIST1H2BH; ALX1
    protein homodimerization activity ATF3; UPK1A; CADM3; DMRTC2; S100A11; ZHX3; BOK; QPRT; PVRL3; ALDH5A1
    transferrin receptor binding HFE2; SNX2; RGMA; TF; HFE; Trf; SNX4; SNX1; CD81

    SNX1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SNX1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SNX1.

    ARL6IP1; SNX32; REEP6; pi3p; RTN3

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