• Official Full Name

    sorting nexin 1

  • Overview

    This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This endosomal protein regulates the cell-surface expression of epidermal growth factor receptor. This protein also has a role in sorting protease-activated receptor-1 from early endosomes to lysosomes. This protein may form oligomeric complexes with family members. This gene results in three transcript variants encoding distinct isoforms.
  • Synonyms

    SNX1; sorting nexin 1; sorting nexin-1; HsT17379; MGC8664; SNX1A; Vps5; sorting nexin 1A;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Cynomolgus Monkey
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • GST
  • His
  • His (Fc)
  • Avi
  • SUMO
  • Myc
  • DDK
  • N/A
  • N
  • T7
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SNX1-30609TH Recombinant Human SNX1, His-tagged E.coli His 377 amino acids
Human SNX1-30610TH Recombinant Human SNX1, T7 -tagged E.coli T7
Human SNX1-2991H Recombinant Human Sorting Nexin 1, T7-tagged E.coli T7
Human SNX1-2800H Recombinant Human Sorting Nexin 1, His-tagged E.coli His
Human SNX1-1605HCL Recombinant Human SNX1 293 Cell Lysate HEK293 N/A
Human SNX1-4439H Recombinant Human SNX1 protein, His-SUMO-tagged E.coli His-SUMO 1-522aa
Human SNX1-800H Recombinant Human SNX1 protein, His-tagged E.coli His 81-287 aa
Human SNX1-3623H Recombinant Human SNX1 protein, GST-tagged E.coli GST 81-287 aa
Human SNX1-2309H Recombinant Human SNX1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human SNX1-2717H Recombinant Human SNX1 Protein, His-tagged E.coli N-His Met1-Ser522
Mouse Snx1-6019M Recombinant Mouse Snx1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat SNX1-5652R Recombinant Rat SNX1 Protein Mammalian Cell His
Rat SNX1-5311R Recombinant Rat SNX1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat SNX1-5311R-B Recombinant Rat SNX1 Protein Pre-coupled Magnetic Beads HEK293
Cynomolgus Monkey SNX1-953C Recombinant Cynomolgus SNX1 Protein, His-tagged Mammalian Cell His
Cynomolgus Monkey SNX1-696C-B Recombinant Cynomolgus Monkey SNX1 Protein Pre-coupled Magnetic Beads HEK293
Cynomolgus Monkey SNX1-696C Recombinant Cynomolgus Monkey SNX1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque SNX1-4386R Recombinant Rhesus monkey SNX1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque SNX1-4202R Recombinant Rhesus Macaque SNX1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque SNX1-4202R-B Recombinant Rhesus Macaque SNX1 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein

SNX1 involved in several pathways and played different roles in them. We selected most pathways SNX1 participated on our site, such as Endocytosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with SNX1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

SNX1 has several biochemical functions, for example, epidermal growth factor receptor binding, identical protein binding, insulin receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SNX1 itself. We selected most functions SNX1 had, and list some proteins which have the same functions with SNX1. You can find most of the proteins on our site.

Function Related Protein
epidermal growth factor receptor bindingPLSCR1;BTC;EGF;TGFA;HBEGF;MS4A1;EFEMP1;ATXN2;YES1
identical protein bindingCLDN9;B2M;PPP5C;LECT2;VPS4B;IK;ORAI1;SEPT7;DAPK3
insulin receptor bindingLMBRD1;PTPN1;DOK7;SNX1;IGF1;PTPN11;DOK3;SHC1;IGF1R
leptin receptor bindingSNX1;SNX2;SNX4
phosphatidylinositol bindingZCCHC2;SGK3;NOXO1;ING2;TULP4;PIK3C2B;NOXO1A;HIP1;ARHGAP33
protein bindingFAM189B;HTRA2;C5;ENOX1;C6orf211;BLOC1S3;LPHN1;PCTP;SLC22A2
protein heterodimerization activityHIST1H2BM;TENM1;NOTCH4;SOX15;DMRT1;BIRC5;OSTB;SAE1;EXT1
protein homodimerization activityBNIP3L;HRSP12;TFAP2B;SYT10;GOLGA5;HMGCS1;MID2;GABPB2;KCNK3
transferrin receptor bindingSNX1;SNX2;SNX4;CD81;HFE2;HFE;TF;Trf;RGMA

SNX1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SNX1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SNX1.

ARL6IP1; SNX32; REEP6; pi3p; RTN3

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