- Involved Pathway
- Protein Function
- Interacting Protein
- STAT5B Related Articles
- STAT5B Related Gene Family
- STAT5B Related Signal Pathway
STAT5B involved in several pathways and played different roles in them. We selected most pathways STAT5B participated on our site, such as ErbB signaling pathway, Chemokine signaling pathway, Jak-STAT signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with STAT5B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
||Pathway Related Protein
|ErbB signaling pathway||ABL2;PLCG2;PAK7;PIK3CG;CAMK2G1;GRB2B;EGFRA;CAMK2D;CDKN1BB|
|Chemokine signaling pathway||CCR10;XCL2;RELA;FGR;VAV1;PAK1;RHOA;NFKBIB;CXCR5|
|Jak-STAT signaling pathway||PIK3R3B;JAK2B;CSH;PIAS4B;AOX1;IL13RA2;IL28A;PIAS2;IFNA8|
|Prolactin signaling pathway||STAT3;STAT1;ELF5;SOCS1;LHB;CSN2;AKT2;MAP2K2;IRF1|
|HTLV-I infection||DLG1;IKBKG;CD3E; CD3D;TNFRSF13C;RANBP3;WNT8A;APC2;HRAS;SFPI1|
|Pathways in cancer||WNT8A;PTEN;BAX;LAMA5;PTGER4;ROCK1;LAMB2;RASSF5;WNT2B|
|Chronic myeloid leukemia||TGFBR1;CCND1;HRAS;RB1;PIK3R1;PIK3R5;HDAC2;TGFB2;ABL1|
|Acute myeloid leukemia||MAPK1;PIK3R1;MAP2K2;HRAS;AKT3;BAD;IKBKB;PIK3CG;MYC|
STAT5B has several biochemical functions, for example, DNA binding, chromatin binding, glucocorticoid receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by STAT5B itself. We selected most functions STAT5B had, and list some proteins which have the same functions with STAT5B. You can find most of the proteins on our site.
|glucocorticoid receptor binding||NRIP1;STAT5B;STAT3;YWHAH;EP300;GRIP1;CEBPB;NR4A2;FKBP4|
|protein dimerization activity||TFE3A;POLR1C;NUP210;MEF2CA;HER4.2;CLOCKA;NHLH2;ZBED1;MYCH|
|signal transducer activity||GPR82;VMN1R43;PRMT2;F2RL2;GNAO1B;GNAO1A;GNAO1;Fzd4;CTNNB2|
|transcription factor activity, sequence-specific DNA binding||HNF1A;KLF11;RORAB;BACH2;ZKSCAN17;SMAD5;RARA;SOX21;INSM1A|
STAT5B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with STAT5B here. Most of them are supplied by our site. Hope this information will be useful for your research of STAT5B.
NMI; VCAM1; STAP2
Zhang, Q; Wang, HY; et al. Cutaneous T Cell Lymphoma Expresses Immunosuppressive CD80 (B7-1) Cell Surface Protein in a STAT5-Dependent Manner. JOURNAL OF IMMUNOLOGY 192:2913-2919(2014).
Atkinson, TP; et al. Immune deficiency and autoimmunity. CURRENT OPINION IN RHEUMATOLOGY 24:515-521(2012).