thbs2

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thbs2

Official Full Name thrombospondin 2
Background The protein encoded by this gene belongs to the thrombospondin family. It is a disulfide-linked homotrimeric glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. This protein has been shown to function as a potent inhibitor of tumor growth and angiogenesis. Studies of the mouse counterpart suggest that this protein may modulate the cell surface properties of mesenchymal cells and be involved in cell adhesion and migration. [provided by RefSeq, Jul 2008]
Synonyms THBS2; thrombospondin 2; TSP2; thrombospondin-2;
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Mammalian cells
    • Yeast
    • Tag :
    • His
    • GST
    • T7
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human THBS2-101H Recombinant Human THBS2, His-tagged Mammalian cells His
    Human THBS2-1100HCL Recombinant Human THBS2 293 Cell Lysate HEK293 N/A
    Human THBS2-8253H Recombinant Human THBS2 protein, His & T7-tagged E.coli His/T7
    Mouse THBS2-1539M Recombinant Mouse THBS2 Protein (19-232 aa), His-tagged Yeast His
    Mouse THBS2-16737M Recombinant Mouse THBS2 Protein Mammalian Cell His
    Mouse Thbs2-8254M Recombinant Mouse Thbs2 protein, His & GST-tagged E.coli His/GST
    Mouse THBS2-830M Recombinant Mouse THBS2 Protein (19-232 aa), His-tagged E.coli His
    Rat Thbs2-1770R Recombinant Rat Thbs2 protein, His & GST-tagged E.coli His/GST
    Chicken THBS2-1151C Recombinant Chicken THBS2 Mammalian Cell His

    thbs2 involved in several pathways and played different roles in them. We selected most pathways thbs2 participated on our site, such as Phagosome, PIK-Akt signaling pathway, Focal adhesion, which may be useful for your reference. Also, other proteins which involved in the same pathway with thbs2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Phagosome SFTPD; CTSSB.1; C1R; CALRL2; CCDC102A; MHC2A; TAP2; FCAR; ITGA2; CLEC7A
    PIK-Akt signaling pathway G6PC; LAMB3; Fgf15; ITGA9; ITGA4; HGF; LAMB2; NR4A1; INS1; ITGB5
    Focal adhesion ITGB1; MYL9A; FYNA; VCL; ROCK2A; DIAP1; PAK2A; COL4A2; COMP; THBS3A
    ECM-receptor interaction COL2A1B; COL4A6; ITGA2; LAMB1; THBS2; THBS1; ITGA6B; HSPG2; LAMA5; SPP1
    Malaria KLRK1; CD40LG; TLR2; THBS3; VCAM1; KLRC4-KLRK1; THBS4; MET; CD40; TGFB2

    thbs2 has several biochemical functions, for example, calcium ion binding, heparin binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by thbs2 itself. We selected most functions thbs2 had, and list some proteins which have the same functions with thbs2. You can find most of the proteins on our site.

    Function Related Protein
    calcium ion binding ASPH; CDH3; SYT5B; SYTL2; CDH7; FBLN7; S100A16; SYT5A; PCDHB2; CAPN9
    heparin binding FGF14; CRISPLD2; APLP2; FGFR1A; NRP1A; EPYC; APOE; PCOLCE2; CCL23; LTBP2
    protein binding GAK; RPS10; BOC; EIF3A; FLAD1; EVLA; C17orf81; FAM120B; SOX-2; EHD1

    thbs2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with thbs2 here. Most of them are supplied by our site. Hope this information will be useful for your research of thbs2.

    Cacna2d1

    Lin, D; Alborn, WE; et al. Comparison of Protein Immunoprecipitation-Multiple Reaction Monitoring with ELISA for Assay of Biomarker Candidates in Plasma. JOURNAL OF PROTEOME RESEARCH 12:5996-6003(2013).
    Czekierdowski, A; Czekierdowska, S; et al. MICROVESSEL DENSITY AND CPG ISLAND METHYLATION OF THBS2 GENE IN MALIGNANT OVARIAN TUMORS. JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY 59:53-65(2008).

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