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TNFAIP6

  • Official Full Name

    tumor necrosis factor, alpha-induced protein 6

  • Overview

    The protein encoded by this gene is a secretory protein that contains a hyaluronan-binding domain, and thus is a member of the hyaluronan-binding protein family. The hyaluronan-binding domain is known to be involved in extracellular matrix stability and cell migration. This protein has been shown to form a stable complex with inter-alpha-inhibitor (I alpha I), and thus enhance the serine protease inhibitory activity of I alpha I, which is important in the protease network associated with inflammation. This gene can be induced by proinflammatory cytokines such as tumor necrosis factor alpha and interleukin-1. Enhanced levels of this protein are found in the synovial fluid of patients with osteoarthritis and rheumatoid arthritis.
  • Synonyms

    TNFAIP6; tumor necrosis factor, alpha-induced protein 6; tumor necrosis factor-inducible gene 6 protein; TSG 6; TSG6; Hyaluronate binding protein; TNF stimulated gene 6 protein; TNFAIP 6; Tumor necrosis factoralpha induced protein 6; Tumor necrosis factor alpha induced protein 6; Tumor necrosis factor stimulated gene 6 protein; OTTHUMP00000162710; TNF alpha-induced protein 6; hyaluronate-binding protein; TNF-stimulated gene 6 protein; tumor necrosis factor alpha-inducible protein 6; tumor necrosis factor-stimulated gene-6 protein; TSG-6;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • E. coli
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Insect Cell
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • His|T7
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human TNFAIP6-42H Active Recombinant Human TNFAIP6 protein, His-tagged Mammalian cells His
Human TNFAIP6-3315H Recombinant Human TNFAIP6, His-tagged E.coli His 1-277aa
Human TNFAIP6-3005H Recombinant Human TNFAIP6 protein, GST-tagged Wheat Germ GST
Human TNFAIP6-3004H Recombinant Human Tumor Necrosis Factor, Alpha-Induced Protein 6, His-tagged E.coli His
Human TNFAIP6-896HCL Recombinant Human TNFAIP6 293 Cell Lysate HEK293 N/A
Human TNFAIP6-2263H Recombinant Human TNFAIP6 protein, His&Myc-tagged Insect Cell His&Myc 18-277aa
Human TNFAIP6-4225H Recombinant Human TNFAIP6 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human TNFAIP6-578HF Recombinant Full Length Human TNFAIP6 Protein, GST-tagged In Vitro Cell Free System GST 277 amino acids
Human TNFAIP6-4225H-B Recombinant Human TNFAIP6 Protein Pre-coupled Magnetic Beads HEK293
Mouse Tnfaip6-916M Active Recombinant Mouse Tnfaip6 Protein, His-tagged Mammalian cells His Trp18-Leu275
Mouse TNFAIP6-17146M Recombinant Mouse TNFAIP6 Protein Mammalian Cell His
Mouse TNFAIP6-9470M-B Recombinant Mouse TNFAIP6 Protein Pre-coupled Magnetic Beads HEK293
Mouse Tnfaip6-1417M Recombinant Mouse Tnfaip6 protein, His & T7-tagged E.coli His/T7 Trp18~Leu275 (Accession # O08859)
Mouse TNFAIP6-25M Recombinant Mouse TNFAIP6 Protein, His-tagged E. coli His
Mouse TNFAIP6-9470M Recombinant Mouse TNFAIP6 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Tnfaip6-9471M Recombinant Mouse Tnfaip6 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Tnfaip6-9471M-B Recombinant Mouse Tnfaip6 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque TNFAIP6-4863R Recombinant Rhesus monkey TNFAIP6 Protein, His-tagged Mammalian Cell His
Rhesus Macaque TNFAIP6-4677R-B Recombinant Rhesus Macaque TNFAIP6 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque TNFAIP6-4677R Recombinant Rhesus Macaque TNFAIP6 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish TNFAIP6-3730Z Recombinant Zebrafish TNFAIP6 Mammalian Cell His
Chicken TNFAIP6-3306C Recombinant Chicken TNFAIP6 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • TNFAIP6 Related Articles
  • TNFAIP6 Related Research Area

TNFAIP6 involved in several pathways and played different roles in them. We selected most pathways TNFAIP6 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with TNFAIP6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

TNFAIP6 has several biochemical functions, for example, hyaluronic acid binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TNFAIP6 itself. We selected most functions TNFAIP6 had, and list some proteins which have the same functions with TNFAIP6. You can find most of the proteins on our site.

Function Related Protein
hyaluronic acid bindingSTAB2;IMPG2;CD44;VCAN;LAYN;KIAA1199;NCAN;ACAN;TNFAIP6

TNFAIP6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TNFAIP6 here. Most of them are supplied by our site. Hope this information will be useful for your research of TNFAIP6.

Jang, YJ; Park, JI; et al. Cumulus Cell-Expressed Type I Interferons Induce Cumulus Expansion in Mice. BIOLOGY OF REPRODUCTION 92:-(2015).
Anderson, RA; Bayne, RAL; et al. Brain-derived neurotrophic factor is a regulator of human oocyte maturation and early embryo development. FERTILITY AND STERILITY 93:1394-1406(2010).
Nagyova, E; Camaioni, A; et al. Synthesis of tumor necrosis factor alpha-induced protein 6 in porcine preovulatory follicles: A study with A38 antibody. BIOLOGY OF REPRODUCTION 78:903-909(2008).
  • Q&As
  • Reviews

Q&As (5)

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How does TNFAIP6 interact with other proteins in the inflammatory cascade? 01/13/2022

TNFAIP6 interacts with various proteins involved in the inflammatory cascade, exerting its anti-inflammatory effects by modulating cytokines and growth factors.

In what ways does TNFAIP6 influence cell migration? 06/05/2021

TNFAIP6 has been shown to influence cell migration, a critical aspect of tissue repair, by regulating the interactions between cells and the extracellular matrix.

How does TNFAIP6 contribute to tissue repair? 06/09/2020

TNFAIP6 plays a crucial role in tissue repair by modulating the activity of hyaluronic acid, which is involved in tissue regeneration and wound healing.

Are there therapeutic applications of TNFAIP6 in tissue regeneration? 10/30/2019

Studies are exploring the therapeutic potential of TNFAIP6 in promoting tissue regeneration, particularly in the context of joint and cartilage repair.

Can TNFAIP6 be used as a biomarker for inflammatory diseases? 04/18/2017

Research suggests that TNFAIP6 levels may serve as a potential biomarker for certain inflammatory conditions, aiding in diagnosis and monitoring disease progression.

Customer Reviews (3)

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Reviews
08/01/2020

    Tthe manufacturer's commitment to exceptional technical support offers me peace of mind, knowing that any challenges or concerns I may encounter will be effectively addressed. he manufacturer's commitment to exceptional technical support offers me peace of mind, knowing that any challenges or concerns I may encounter will be effectively addressed.

    05/18/2016

      Its high specificity and robust activity make it an ideal candidate for investigating intricate molecular interactions and elucidating complex biological mechanisms.

      04/11/2016

        With the TNFAIP6 protein, I can confidently pursue my scientific objectives and overcome experimental obstacles, enabling me to make significant strides in my field of study.

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