Recombinant Human TNFRSF10A protein, His-Avi-tagged, Biotinylated

• Cat.No.: TNFRSF10A-212HB
• Product Overview: Biotinylated Recombinant Human TRAIL R1 / DR4 / TNFRSF10A Protein is expressed from mammalian with His Tag and Avi Tag at the C-terminal. It contains Pro34-Asn 239.

Specification

• Description: Tumor necrosis factor receptor superfamily member 10A (TNFRSF10A) is also known as TNF-related apoptosis-inducing ligand receptor 1 (TRAIL-R1), Death receptor 4 (DR4), CD261 and APO2, which belongs to TNF superfamily.The expression of apoptosis-inducing TRAIL-R1 and TRAIL-R2 and of the decoy receptors TRAIL-R3 and TRAIL-R4 was systematically studied in all developmental stages of peripheral B cells isolated from the blood and secondary lymphoid organs. Expression of TRAIL-Rs is modulated along development, with highest levels observed in germinal center B cells.
• Source: HEK293
• Species: Human
• Tag: His-Avi
• Form: Supplied as 0.22um filtered solution in PBS (pH 7.4).
• Molecular Mass: The protein has a predicted MW of 24.7 KDa. Due to glycosylation, the protein migrates to 25-30KDa based on Bis-Tris PAGE result.
• Protein length: It contains Pro34-Asn 239.
• Endotoxin: Less than 0.1EU per ug by the LAL method.
• Purity: > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
• Storage: The product should be stored at -70°C. Please do not repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.

Gene Information

• Gene Name: TNFRSF10A tumor necrosis factor receptor superfamily, member 10a [ Homo sapiens ]
• Official Symbol: TNFRSF10A
• Synonyms: DR4;CD261;TNFRSF10A;TRAIL-R;APO2;TRAIL R1
• Gene ID: 8797
• mRNA Refseq: NM_003844
• Protein Refseq: NP_003835
• MIM: 603611
• UniProt ID: O00220