TOR1A
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Official Full Name
torsin family 1, member A (torsin A) -
Overview
The protein encoded by this gene is a member of the AAA family of adenosine triphosphatases (ATPases), is related to the Clp protease/heat shock family and is expressed prominently in the substantia nigra pars compacta. Mutations in this gene result in the autosomal dominant disorder, torsion dystonia 1. [provided by RefSeq, Jul 2008] -
Synonyms
TOR1A;torsin family 1, member A (torsin A);DQ2;DYT1;torsin-1A;torsin ATPase 1;dystonia 1 protein;torsin family 1 member A;dystonia 1, torsion (autosomal dominant;torsin A)
Recombinant Proteins
- Human
- Mouse
- Cynomolgus
- Chicken
- E.coli
- Mammalian Cells
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- GST
- His
- Non
- DDK
- Myc
- Avi
- Fc
Involved Pathway
TOR1A involved in several pathways and played different roles in them. We selected most pathways TOR1A participated on our site, such as Alpha-synuclein signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with TOR1A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Alpha-synuclein signaling | STUB1,BLK,CSNK2A1,KLK6,PARK7,FKBP1A |
Protein Function
TOR1A has several biochemical functions, for example, ATP binding,ATPase activity,cytoskeletal protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TOR1A itself. We selected most functions TOR1A had, and list some proteins which have the same functions with TOR1A. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| kinesin binding | KIF1B,SNCA,KIAA1279,AP1AR,JAKMIP1,CD36,KIF18B,KLC2,CLSTN1,PPIAL4A |
| cytoskeletal protein binding | ACTN2,FRMD3,EPB41L5,PDLIM3,EPB4.1L4A,FARP1,DES,PACSIN2,MSNA,TPM1 |
| ATPase activity | EIF4A2,ABCA5,ABCA9,NSF,KIF15,KIF2B,PICK1,DNAH6,PSMC6,ABCA13 |
| protein binding | KRT6C,RPL23,ZBED1,NLK,NOS1,LPL,ISCU,Ctsl,RXRB,KLK8 |
| ATP binding | NEK7,KIF19,ACSM2B,DNAJA3,UBE2D1A,PANK4,HIPK3,AURKB,HSPA2,MAPK8 |
| unfolded protein binding | TMEM67,ERLEC1,CLN3,TTC1,CRYABA,DNAJA3,SIL1,HSPA1L,HSP90B1,GRPEL2 |
| misfolded protein binding | HSPA5,DNAJB9,STUB1,SDF2L1,BAG6,HSPD1,DNAJC3,DNAJC10,EDEM1,F12 |
Interacting Protein
TOR1A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TOR1A here. Most of them are supplied by our site. Hope this information will be useful for your research of TOR1A.
KRTAP10-7;LRRC7;DYNC1H1;TOR1AIP2;CNIH4;DHCR7;Hsp90b1;Dnajb11;env;H2AFX;COPS4
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