Recombinant Human TOR1A Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: TOR1A-454H
• Product Overview: TOR1A MS Standard C13 and N15-labeled recombinant protein (NP_000104) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: The protein encoded by this gene is a member of the AAA family of adenosine triphosphatases (ATPases), is related to the Clp protease/heat shock family and is expressed prominently in the substantia nigra pars compacta. Mutations in this gene result in the autosomal dominant disorder, torsion dystonia 1.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 37.8 kDa
• AA Sequence: MKLGRAVLGLLLLAPSVVQAVEPIS LGLALAGVLTGYIYPRLYCLFAECC GQKRSLSREALQKDLDDNLFGQHLA KKIILNAVFGFINNPKPKKPLTLSL HGWTGTGKNFVSKIIAENIYEGGLN SDYVHLFVATLHFPHASNITLYKDQ LQLWIRGNVSACARSIFIFDEMDKM HAGLIDAIKPFLDYYDLVDGVSYQK AMFIFLSNAGAERITDVALDFWRSG KQREDIKLKDIEHALSVSVFNNKNS GFWHSSLIHRNLIDYFVPFLPLEYK HLKMCIRVEMQSRGYEIDEDIVSRV AEEMTFFPKEERVFSDKGCKTVFTK LDYYYDDSGPTRTRPLEQKLISEED LAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: TOR1A torsin family 1 member A [ Homo sapiens (human) ]
• Official Symbol: TOR1A
• Synonyms: TOR1A; torsin family 1, member A (torsin A); dystonia 1, torsion (autosomal dominant; torsin A), DYT1; torsin-1A; DQ2; dystonia 1 protein; torsin family 1 member A; dystonia 1, torsion (autosomal dominant; torsin A); DYT1
• Gene ID: 1861
• mRNA Refseq: NM_000113
• Protein Refseq: NP_000104
• MIM: 605204
• UniProt ID: O14656