TREML1

  • Official Full Name

    triggering receptor expressed on myeloid cells-like 1

  • Overview

    TREML1 is located in a gene cluster on chromosome 6 with the single Ig variable (IgV) domain activating receptors TREM1;(MIM 605085) and TREM2 (MIM 605086), but it has distinct structural and functional properties. TREML1 enhances calcium;signaling in an SHP2 (PTPN11; MIM 176876)-dependent manner (Allcock et al., 2003 (PubMed 12645956); Barrow et al.,;2004 (PubMed 15128762)).
  • Synonyms

    TREML1; triggering receptor expressed on myeloid cells-like 1; trem-like transcript 1 protein; dJ238O23.3; TLT1; TREM like transcript 1; triggering receptor expressed on myeloid cells-like protein 1; TLT-1; PRO3438; GLTL1825; MGC119173;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rhesus Macaque
  • E.coli
  • HEK293
  • HEK293T
  • Human Cell
  • Mammalian Cell
  • Mammalian cells
  • Fc
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • Myc|DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human TREML1-3401H Recombinant Human TREML1, GST-tagged E.coli GST
Human TREML1-373H Recombinant Human TREML1 Protein, Fc-tagged HEK293 Fc
Human TREML1-3943H Recombinant Human TREML1, His-tagged HEK293 His
Human TREML1-2084HCL Recombinant Human TREML1 cell lysate Human Cell N/A
Human TREML1-2512H Recombinant Human TREML1 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human TREML1-1567H Recombinant Human TREML1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Mouse Treml1-398M Active Recombinant Mouse Treml1, His-tagged Mammalian cells His
Mouse TREML1-17322M Recombinant Mouse TREML1 Protein Mammalian Cell His
Mouse TREML1-9579M-B Recombinant Mouse TREML1 Protein Pre-coupled Magnetic Beads HEK293
Mouse TREML1-9579M Recombinant Mouse TREML1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Treml1-6635M Recombinant Mouse Treml1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse Treml1-9580M Recombinant Mouse Treml1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Treml1-9580M-B Recombinant Mouse Treml1 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque TREML1-4949R Recombinant Rhesus monkey TREML1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque TREML1-4763R Recombinant Rhesus Macaque TREML1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque TREML1-4763R-B Recombinant Rhesus Macaque TREML1 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • TREML1 Related Articles
  • TREML1 Related Research Area

TREML1 involved in several pathways and played different roles in them. We selected most pathways TREML1 participated on our site, such as Adaptive Immune System, Immune System, Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell, which may be useful for your reference. Also, other proteins which involved in the same pathway with TREML1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Adaptive Immune SystemLILRB2;CD300A;ASB18;CLEC2H;AP2B1;KIR2DS2;CREB1B;MOV10;AGO2
Immune SystemKIF11;SIGIRR;ASB13;IL1RN;IFIT3;CMTM2A;HCST;KIFAP3;DDOST
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cellLILRB2;SH2D1B;Mill2;CLEC2H;CD300A;HCST;SIGLEC10;AMICA1;OSCAR

TREML1 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TREML1 itself. We selected most functions TREML1 had, and list some proteins which have the same functions with TREML1. You can find most of the proteins on our site.

Function Related Protein
protein bindingEPHB1;SYCE2;LIN9;PAF1;CSRP3;PHLPP1;FAM113A;DDAH2;ATP1A1

TREML1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TREML1 here. Most of them are supplied by our site. Hope this information will be useful for your research of TREML1.

Esponda, OL; Hunter, R; et al. Levels of Soluble TREM-Like Transcript 1 in Patients Presenting to the Emergency Department With Chest Pain. CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS 21:30-34(2015).
Yoon, SH; Lee, YD; et al. TLT-1s, Alternative Transcripts of Triggering Receptor Expressed on Myeloid Cell-like Transcript-1 (TLT-1), Inhibits the Triggering Receptor Expressed on Myeloid Cell-2 (TREM-2)-mediated Signaling Pathway during Osteoclastogenesis. JOURNAL OF BIOLOGICAL CHEMISTRY 287:29620-29626(2012).
  • Q&As
  • Reviews

Q&As (1)

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How is TREML1 linked to the regulation of immune checkpoints? 02/21/2019

TREML1 has been implicated in the regulation of immune checkpoints, influencing the balance of immune responses and potential applications in cancer immunotherapy.

Customer Reviews (3)

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Reviews
11/22/2020

    Its purity and consistency guarantee accurate and consistent results, allowing for confident data interpretation and analysis.

    08/26/2020

      The exceptional quality and reliability of the TREML1 protein provided by the manufacturer cannot be overstated.

      06/05/2018

        the manufacturer's dedication to continuous improvement and innovation is evident in their ongoing efforts to enhance the TREML1 protein's performance and optimize its applications.

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