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Official Full Name thioredoxin domain containing 12 (endoplasmic reticulum)
Background This gene encodes a member of the thioredoxin superfamily. Members of this family are characterized by a conserved active motif called the thioredoxin fold that catalyzes disulfide bond formation and isomerization. This protein localizes to the endoplasmic reticulum and has a single atypical active motif. The encoded protein is mainly involved in catalyzing native disulfide bond formation and displays activity similar to protein-disulfide isomerases. This protein may play a role in defense against endoplasmic reticulum stress. Alternate splicing results in both coding and non-coding variants.
Synonyms TXNDC12; thioredoxin domain containing 12 (endoplasmic reticulum); thioredoxin domain-containing protein 12; AGR1; anterior gradient homolog 1 (Xenopus laevis); endoplasmic reticulum thioredoxin superfamily member; 18 kDa; ERP18; ERP19; hAG 1; PDIA16; pro
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Yeast
    • Tag :
    • His
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human TXNDC12-3497H Recombinant Human TXNDC12, His-tagged E.coli His
    Human TXNDC12-3498H Recombinant Human TXNDC12, His-tagged HEK293 His
    Human TXNDC12-6147H Recombinant Human TXNDC12 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human TXNDC12-626HCL Recombinant Human TXNDC12 293 Cell Lysate HEK293 N/A
    Human TXNDC12-6840H Recombinant Human Thioredoxin Domain Containing 12 (endoplasmic reticulum), His-tagged E.coli His
    Mouse TXNDC12-1870M Recombinant Mouse TXNDC12 Protein (25-170 aa), His-tagged E.coli His
    Mouse TXNDC12-1925M Recombinant Mouse TXNDC12 Protein (25-170 aa), His-tagged Yeast His
    Mouse Txndc12-6746M Recombinant Mouse Txndc12 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Rat TXNDC12-6373R Recombinant Rat TXNDC12 Protein Mammalian Cell His
    Rhesus Macaque TXNDC12-5037R Recombinant Rhesus monkey TXNDC12 Protein, His-tagged Mammalian Cell His
    Chicken TXNDC12-5449C Recombinant Chicken TXNDC12 Mammalian Cell His
    Zebrafish TXNDC12-2941Z Recombinant Zebrafish TXNDC12 Mammalian Cell His

    txndc12 involved in several pathways and played different roles in them. We selected most pathways txndc12 participated on our site, such as Glutathione metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with txndc12 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Glutathione metabolism GSTAL; GPX3; GGT6; GSTM4; GPX4; GPX5; GSTK1; GGCT; GPX8; GCLC

    txndc12 has several biochemical functions, for example, peptide disulfide oxidoreductase activity, protein binding, protein-disulfide reductase (glutathione) activity. Some of the functions are cooperated with other proteins, some of the functions could acted by txndc12 itself. We selected most functions txndc12 had, and list some proteins which have the same functions with txndc12. You can find most of the proteins on our site.

    Function Related Protein
    peptide disulfide oxidoreductase activity TXNDC12; TXN; Txn1
    protein binding MFAP1; JMJD7; PPP6R2; BIN1; MEPE; CCL4; SYT2; TUBGCP4; ATG12; LBP
    protein-disulfide reductase (glutathione) activity TXNDC12

    txndc12 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with txndc12 here. Most of them are supplied by our site. Hope this information will be useful for your research of txndc12.


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