Recombinant Human UBE2M, His-tagged

• Cat.No.: UBE2M-135H
• Product Overview: Recombinant Human UBE2M, fused with His tag, was expressed in E.coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Form: Liquid, 50 mM Tris, pH 7.5; 150 mM NaCl; 10 mM DTT; 10% glycerol
• Molecular Mass: 21894.2 Da by MS (calculated 21894)
• Purity: >90% by RP-HPLC
• Applications: Ubiquitin ligation reactions
• Storage: Store at -80℃. Avoid repeated freeze/thaw cycles.

Gene Information

• Gene Name: UBE2M ubiquitin-conjugating enzyme E2M [ Homo sapiens ]
• Official Symbol: UBE2M
• Synonyms: UBE2M; ubiquitin-conjugating enzyme E2M; ubiquitin conjugating enzyme E2M (homologous to yeast UBC12) , ubiquitin conjugating enzyme E2M (UBC12 homolog, yeast); NEDD8-conjugating enzyme Ubc12; hUbc12; UBC12; yeast UBC12 homolog; NEDD8 protein ligase; NEDD8 carrier protein; ubiquitin-protein ligase M; ubiquitin carrier protein M; ubiquitin-conjugating enzyme E2M (UBC12 homolog, yeast); UBC-RS2
• Gene ID: 9040
• mRNA Refseq: NM_003969
• Protein Refseq: NP_003960
• MIM: 603173
• UniProt ID: P61081
• Chromosome Location: 19q13.43
• Pathway: Adaptive Immune System, organism-specific biosystem; Antigen processing: Ubiquitination and Proteasome degradation, organism-specific biosystem; Class I MHC mediated antigen processing & presentation, organism-specific biosystem; Immune System, organism-specific biosystem; Ubiquitin mediated proteolysis, organism-specific biosystem
• Function: ATP binding; NEDD8 ligase activity; acid-amino acid ligase activity; ligase activity; nucleotide binding; protein binding; ribosomal S6-glutamic acid ligase activity; ubiquitin-protein ligase activity; ubiquitin-protein ligase activity