UGT2B7 Protein

Home / Products / UGT2B7

UGT2B7

Official Full Name	UDP glucuronosyltransferase 2 family, polypeptide B7
Background	The protein encoded by this gene belongs to the UDP-glycosyltransferase (UGT) family. UGTs serve a major role in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This protein is localized in the microsome membrane, and has unique specificity for 3,4-catechol estrogens and estriol, suggesting that it may play an important role in regulating the level and activity of these potent estrogen metabolites.
Synonyms	UGT2B7; UDP glucuronosyltransferase 2 family, polypeptide B7; UDP glycosyltransferase 2 family, polypeptide B7; UDP-glucuronosyltransferase 2B7; UGT2B9; 3 4 catechol estrogen specific; UDP glucuronosyltransferase 2 family polypeptide B7; UDP glucuronosyltransferase 2B7; UDP glucuronyltransferase family 2 beta 7; UDP glycosyltransferase 2 family polypeptide B7; UDPGT; UDPGTh 2; UDPGTh2; UGTB2B9; UDPGTh-2; UDPGT 2B7; 3,4-catechol estrogen specific; UDP-glucuronosyltransferase 2B9; 3,4-catechol estrogen-specific UDPGT; UDP-glucuronyltransferase, family 2, beta-7; UDPGT2B7; UDPGT 2B9

Type:
Recombinant Proteins

Species :
Homo sapiens (Human)
Human
Rat
Rattus norvegicus (Rat)

Source :
E.coli
E.coli expression system
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag :
GST
His
N-His

Species	Cat.#	Product name	Source (Host)	Tag	Price
Human	UGT2B7-209H	Recombinant Human UGT2B7, GST-tagged	Wheat Germ	GST	Inquiry
Rat	UGT2B7-6436R	Recombinant Rat UGT2B7 Protein	Mammalian Cell	His	Inquiry
Homo sapiens (Human)	RFL23893HF	Recombinant Full Length Human Udp-Glucuronosyltransferase 2B7(Ugt2B7) Protein, His-Tagged	E.coli expression system	His	Inquiry
Rattus norvegicus (Rat)	RFL26914RF	Recombinant Full Length Rat Udp-Glucuronosyltransferase 2B7(Ugt2B7) Protein, His-Tagged	E.coli expression system	His	Inquiry
Human	UGT2B7-2431H	Recombinant Human UGT2B7 protein, His-tagged	E.coli	His	Inquiry
Human	UGT2B7-536H	Recombinant Human UGT2B7 Protein, His-tagged	E.coli	N-His	Inquiry
Human	UGT2B7-542HF	Recombinant Full Length Human UGT2B7 Protein, GST-tagged	In Vitro Cell Free System	GST	Inquiry
Rat	Ugt2b7-604R	Recombinant Rat Ugt2b7 Protein, His-tagged	E.coli	His	Inquiry

Involved Pathway Protein Function Interacting Protein UGT2B7 Related Articles

UGT2B7 involved in several pathways and played different roles in them. We selected most pathways UGT2B7 participated on our site, such as Pentose and glucuronate interconversions, Ascorbate and aldarate metabolism, Steroid hormone biosynthesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with UGT2B7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Pentose and glucuronate interconversions	CRYL1; UGT2A2; UGT1AB; ALDH2.1; UGT1A7; KL; AKR1A1B; AKR1B1L; AKR1B1; UGT1A6A
Ascorbate and aldarate metabolism	UGT1A9; UGT5G1; UGT2B15; UGDH; UGT2B7; ALDH9A1A.1; RGN; UGT1A2; UGT1A1; UGT1A6A
Steroid hormone biosynthesis	HSD3B1; UGT1A7; SRD5A2A; CYP2C45; CYP7A1A; CYP2C37; UGT5G1; HSD3B5; CYP2C38; CYP1A
Starch and sucrose metabolism	UGP2; GPI1; AMY1B; GYS1; HK1; PGM1; UXS1; HK2; GBE1; UGT1A9
Retinol metabolism	UGT2B7; CYP2C54; UGT1A9; CYP2C39; CYP4A12A; RDH10A; DHRS4; UGT1A3; AOX3; DHRS4L2
Porphyrin and chlorophyll metabolism	UGT2B7; UGT2A1; EPRS; UROD; HMOX2; HMBSB; P22; UGT1A7C; UGT1AB; BLVRA
Metabolism of xenobiotics by cytochrome P	GSTA4; SULT2A1; GSTM4; UGT2B15; GSTA2; CYP2F2; GSTP1; ADH1; ALDH3B1; DHDHL
Drug metabolism - cytochrome P	MGST1; ALDH3B2; GSTT1; UGT1A6B; AOX3; FMO5; UGT2B15; GSTM1; GSTM7; MGST1.1
Drug metabolism - other enzymes	CYP2A6; UGT1A4; Ces2e; CES2; DPYDB; TYMP; HPRT1; UGT2B15; UCK2A; CES1D
Metabolic pathways	HSD17B4; SCP2A; AGPAT3; MOGS; PGAM1A; PFAS; CKMT1B; MTHFD2L; COX6B1; NANP
Chemical carcinogenesis	GSTO2; ADH1B; CYP2C55; SULT1A1; UGT1A9; AHA-1; GSTO1; CYP2C18; CYP2C19; GSTT2B

UGT2B7 has several biochemical functions, for example, glucuronosyltransferase activity, NOT retinoic acid binding. Some of the functions are cooperated with other proteins, some of the functions could acted by UGT2B7 itself. We selected most functions UGT2B7 had, and list some proteins which have the same functions with UGT2B7. You can find most of the proteins on our site.

Function	Related Protein
glucuronosyltransferase activity	UGT2A4; UGT5A5; UGT5G2; CSGALNACT1; UGT5C1; GYLTL1B; EXT1; UGT1B2; UGT5G1; UGT3A1
NOT retinoic acid binding	UGT1A6; UGT2B15; UGT1A4; UGT2B7

UGT2B7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with UGT2B7 here. Most of them are supplied by our site. Hope this information will be useful for your research of UGT2B7.

GABRA3

Fujiwara, R; Itoh, T; et al. Extensive Protein-Protein Interactions Involving UDP-glucuronosyltransferase (UGT) 2B7 in Human Liver Microsomes. DRUG METABOLISM AND PHARMACOKINETICS 29:259-265(2014).

Pazik, J; Oldak, M; et al. Uridine Diphosphate Glucuronosyltransferase 2B7 Variant p.His268Tyr as a Predictor of Kidney Allograft Early Acute Rejection. TRANSPLANTATION PROCEEDINGS 45:1516-1519(2013).

Q&As Reviews

Q&As (0)

Ask a question

UGT2B7

Home / Products / UGT2B7

UGT2B7

Related Services & Products

$50 OFF Your First Purchase

Enter your email here to subscribe.

creative biomart inc.

UGT2B7 Protein

UGT2B7

Home / Products / UGT2B7

UGT2B7

Ask a Question for All UGT2B7 Products

My Review for All UGT2B7 Products

Related Services & Products

$50 OFF Your First Purchase

Enter your email here to subscribe.

creative biomart inc.