Recombinant Human UGT2B7, GST-tagged

Cat.No. : UGT2B7-209H
Product Overview : Recombinant Human UGT2B7(1 a.a. - 529 a.a.), fused with GST-tag at N-terminal, was expressed in wheat germ.
  • Specification
  • Gene Information
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Description : The protein encoded by this gene belongs to the UDP-glycosyltransferase (UGT) family. UGTs serve a major role in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This protein is localized in the microsome membrane, and has unique specificity for 3,4-catechol estrogens and estriol, suggesting that it may play an important role in regulating the level and activity of these potent estrogen metabolites.
Source : Wheat germ
Species : Human
Tag : GST
Molecular Mass : 84.59 kDa
AA Sequence : MSVKWTSVILLIQLSFCFSSGNCGK VLVWAAEYSHWMNIKTILDELIQRG HEVTVLASSASILFDPNNSSALKIE IYPTSLTKTELENFIMQQIKRWSDL PKDTFWLYFSQVQEIMSIFGDITRK FCKDVVSNKKFMKKVQESRFDVIFA DAIFPCSELLAELFNIPFVYSLSFS PGYTFEKHSGGFIFPPSYVPVVMSE LTDQMTFMERVKNMIYVLYFDFWFE IFDMKKWDQFYSEVLGRPTTLSETM GKADVWLIRNSWNFQFPYPLLPNVD FVGGLHCKPAKPLPKEMEDFVQSSG ENGVVVFSLGSMVSNMTEERANVIA SALAQIPQKVLWRFDGNKPDTLGLN TRLYKWIPQNDLLGHPKTRAFITHG GANGIYEAIYHGIPMVGIPLFADQP DNIAHMKARGAAVRVDFNTMSSTDL LNALKRVINDPSYKENVMKLSRIQH DQPVKPLDRAVFWIEFVMRHKGAKH LRVAAHDLTWFQYHSLDVIGFLLVC VATVIFIVTKCCLFCFWKFARKAKK GKND
Applications : ELISA; WB-Re; AP; Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : UGT2B7 UDP glucuronosyltransferase 2 family, polypeptide B7 [ Homo sapiens (human) ]
Official Symbol : UGT2B7
Synonyms : UGT2B7; UDP glucuronosyltransferase 2 family, polypeptide B7; UDP glycosyltransferase 2 family, polypeptide B7; UDP-glucuronosyltransferase 2B7; UGT2B9; 3 4 catechol estrogen specific; UDP glucuronosyltransferase 2 family polypeptide B7; UDP glucuronosyltransferase 2B7; UDP glucuronyltransferase family 2 beta 7; UDP glycosyltransferase 2 family polypeptide B7; UDPGT; UDPGTh 2; UDPGTh2; UGT2B9; UGTB2B9; UDPGTh-2; UDPGT 2B7; 3,4-catechol estrogen specific; UDP glucuronosyltransferase 2B7; UDP-glucuronosyltransferase 2B9; 3,4-catechol estrogen-specific UDPGT; UDP-glucuronyltransferase, family 2, beta-7; UDPGTH2; UDPGT2B7; UDPGT 2B9
Gene ID : 7364
mRNA Refseq : NM_001074
Protein Refseq : NP_001065
MIM : 600068
UniProt ID : P16662
Chromosome Location : 4q13
Pathway : Ascorbate and aldarate metabolism; Chemical carcinogenesis; Codeine and morphine metabolism
Function : glucuronosyltransferase activity; NOT retinoic acid binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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