USP1 Protein


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Official Full Name ubiquitin specific peptidase 1
Background This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. The protein specifically deubiquitinates a protein in the Fanconi anemia (FA) DNA repair pathway. Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008]
Synonyms USP1; ubiquitin specific peptidase 1; UBP; ubiquitin carboxyl-terminal hydrolase 1; hUBP; ubiquitin thioesterase 1; deubiquitinating enzyme 1; ubiquitin thiolesterase 1; ubiquitin specific protease 1; ubiquitin carboxyl terminal hydrolase 1; ubiquitin specific processing protease 1; ubiquitin-specific-processing protease 1;
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Insect Cell
    • Mammalian Cell
    • Sf21 Insect Cell
    • Tag :
    • GST
    • His
    • His (Fc)-Avi
    • T7
    • Myc/DDK
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human USP1&WDR48-1067H Active Recombinant Human USP1&WDR48 Protein, His-tagged Sf21 Insect Cell His Inquiry
    Human USP1-1066H Active Recombinant Human USP1 Protein, His-tagged Sf21 Insect Cell His Inquiry
    Human USP1-3614H Recombinant Human USP1, GST-tagged E.coli GST Inquiry
    Human USP1-955H Recombinant Human USP1, MYC/DDK-tagged HEK293 Myc/DDK Inquiry
    Mouse USP1-17898M Recombinant Mouse USP1 Protein Mammalian Cell His Inquiry
    Rat USP1-6468R Recombinant Rat USP1 Protein Mammalian Cell His Inquiry
    Rat Usp1-7925R Recombinant Rat Usp1 protein, His & T7-tagged E.coli His/T7 Inquiry
    Chicken USP1-2946C Recombinant Chicken USP1 Mammalian Cell His Inquiry
    Zebrafish USP1-9982Z Recombinant Zebrafish USP1 Mammalian Cell His Inquiry
    Human USP1-475HCL Recombinant Human USP1 293 Cell Lysate HEK293 N/A Inquiry
    Rat USP1-6124R Recombinant Rat USP1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi Inquiry
    Human USP1-78H Recombinant Active Human USP1 Protein, GST-tagged Insect Cell GST Inquiry
    Mouse USP1-9946M Recombinant Mouse USP1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi Inquiry
    Human USP1-5563H Recombinant Human USP1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK Inquiry
    Mouse Usp1-6863M Recombinant Mouse Usp1 Protein, Myc/DDK-tagged HEK293T Myc/DDK Inquiry

    USP1 involved in several pathways and played different roles in them. We selected most pathways USP1 participated on our site, such as Fanconi anemia pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with USP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Fanconi anemia pathway FANCB; MUS81; BRCA2; FUZ; ZBTB32; REV3L; FANCA; ERCC4; FANCC; RPA1

    USP1 has several biochemical functions, for example, cysteine-type endopeptidase activity, protein binding, ubiquitin-specific protease activity. Some of the functions are cooperated with other proteins, some of the functions could acted by USP1 itself. We selected most functions USP1 had, and list some proteins which have the same functions with USP1. You can find most of the proteins on our site.

    Function Related Protein
    cysteine-type endopeptidase activity USP20; USP6; CTSJ; CTSL1; ATG4D; CTSM; USP28; CTSLA; CTSS; CTLA2B
    protein binding PSMC3; SP3; FABP1; ABCB9; ZNF543; RPL12; COPS5; PTBP1; TUBA1A; Acr
    ubiquitin-specific protease activity USP27X; OTUD5; USP24; CYLD; UCHL1; USP16; JOSD2; USP12; USP33; OTUD5A

    USP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with USP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of USP1.

    KPNA1; ANXA2P2; c9jh30_human; PHLPP1; HSPB1; JUP; KRT4; FLG; CALML3; MYH9; TAGLN2; LGALS7B; LYZ; DSG1; KRT17; DSC1; USP4; PKP1

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