Recombinant Active Human USP1 Protein, GST-tagged

• Cat.No.: USP1-78H
• Product Overview: Recombinant human full-length USP1 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

Specification

• Description: This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. The protein specifically deubiquitinates a protein in the Fanconi anemia (FA) DNA repair pathway. Alternate transcriptional splice variants have been characterized.
• Source: Insect cell
• Species: Human
• Tag: GST
• Molecular Mass: Approx 130 kDa
• Purity: > 75%
• Stability: One year at -70 centigrade from data of shipment.
• Storage: Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
• Concentration: 0.05 μg/μL
• Storage Buffer: Recombinant protein stored in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 25% glycerol.
• Shipping: Dry ice

Gene Information

• Gene Name: USP1 ubiquitin specific peptidase 1 [ Homo sapiens (human) ]
• Official Symbol: USP1
• Synonyms: USP1; ubiquitin specific peptidase 1; ubiquitin carboxyl-terminal hydrolase 1; Ubiquitinyl hydrolase 1, Ubiquitin carboxyl-terminal hydrolase 1, ubiquitin thiolesterase 1; deubiquitinating enzyme 1; hUBP; ubiquitin specific processing protease 1; ubiquitin specific protease 1; ubiquitin thioesterase 1; ubiquitin thiolesterase 1; EC 3.4.19.12
• Gene ID: 7398
• mRNA Refseq: NM_003368
• Protein Refseq: NP_003359
• MIM: 603478
• UniProt ID: O94782