USP22 involved in several pathways and played different roles in them. We selected most pathways USP22 participated on our site, such as Chromatin modifying enzymes, Chromatin organization, HATs acetylate histones, which may be useful for your reference. Also, other proteins which involved in the same pathway with USP22 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name |
Pathway Related Protein |
| Chromatin modifying enzymes |
SMYD3; KDM4D; DR1; MBD3B; CARM1; SMARCB1; VPS72; BRD8; ING5A; WDR77 |
| Chromatin organization |
PADI6; PHF17; KDM2AA; MEAF6; JMJD6; DPY30; RBBP5; ARID2; ATXN7; BRPF1 |
| HATs acetylate histones |
ZZZ3; KANSL3; ING3; CSRP2BP; DMAP1; EPC1; KANSL2; MSL1; KAT6A; BRD1 |
USP22 has several biochemical functions, for example, contributes_to H4 histone acetyltransferase activity, cysteine-type endopeptidase activity, enzyme binding. Some of the functions are cooperated with other proteins, some of the functions could acted by USP22 itself. We selected most functions USP22 had, and list some proteins which have the same functions with USP22. You can find most of the proteins on our site.
| Function |
Related Protein |
| contributes_to H4 histone acetyltransferase activity |
USP22 |
| cysteine-type endopeptidase activity |
USP18; USP49; USP9; USP1; MALT1A; USP10; USP17L2; USP45; USP2; CASPB |
| enzyme binding |
EGFR; UGT1A6B; ERN1; TULP3; MAT2B; EGLN1; PICK1; PRKCE; PYCARD; DDX5 |
| ligand-dependent nuclear receptor transcription coactivator activity |
PPARGC1B; RBM14; THRAP3; WDR77; HELZ2; MED30; HMGA1; MED4; MED14; PSMC3IP |
| protein binding |
KLK13; EIF3L; ROCK2; UBLCP1; RHOT1; PCBD2; CCND1; MPZL1; MAL; GGPS1 |
| transcription coactivator activity |
RARA; ESRRB; SIX3; LPIN3; CREBBP; STIL; CARM1; E4F1; MKL1B; HCFC1 |
| ubiquitin-specific protease activity |
FMNL3; UCHL5; STAMBP; USP17L5; JOSD2; USP24; USP12; CYLD; USP44; OTUD7B |
| contributes_to ubiquitin-specific protease activity |
ANKZF1; TNIP1; USP22 |
| zinc ion binding |
MGRN1; ZFP37; ZCCHC2; ABP1; SNAI1A; TRIM44; RNF11; PGLYRP5; FTR67; ZBTB32 |
USP22 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with USP22 here. Most of them are supplied by our site. Hope this information will be useful for your research of USP22.
AASDHPPT; FUBP1; CNOT1; USP27X; SUPT3H; TADA3; TAF5L; DEDD; SUPT7L; USP8; NFATC2; ATXN7L3
