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Active Recombinant Human USP22 protein, His-tagged

Cat.No. : USP22-12H
Product Overview : Recombinant Human USP22 protein with his tag at N-terminal was expressed in Sf 21 (baculovirus).
  • Specification
  • Gene Information
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Description : Ubiquitin specific peptidase 22 is a protein that in humans is encoded by the USP22 gene on chromosome 17. USP22 is known to function as a histone deubiquitinating component of the transcription regulatory histone acetylation (HAT) complex SAGA.
Source : Insect cell
Species : Human
Tag : His
Bio-activity : Recombinant human USP22 is a Ubiquitin-specific deconjugating enzyme. Reaction conditions will need to be optimized for each specific application. We recommend an initial USP22 concentration of 20-100 nM when using Ubiquitin-AMC or Ubiquitin-Rhodamine (U-550, U-555) substrates.
Molecular Mass : 59 kDa
Purity : >95%, by SDS-PAGE under reducing conditions
Notes : Recombinant USP22 is not active toward poly-Ubiquitin chains, Ubiquitinated histones and other Ubiquitinated protein substrates in the absence of adapter proteins such as ATXN7L or ENY2.
Storage : 12 months from date of receipt, -70 centigrade as supplied.
3 months, -70 centigrade under sterile conditions after opening.Avoid repeated freeze-thaw cycles.
Gene Name : USP22 ubiquitin specific peptidase 22 [ Homo sapiens (human) ]
Official Symbol : USP22
Synonyms : Deubiquitinating enzyme 22; EC; EC; KIAA1063ubiquitin carboxyl-terminal hydrolase 22; KIAA1064; ubiquitin specific peptidase 22; ubiquitin specific peptidase 3-like; ubiquitin specific protease 22; Ubiquitin Thioesterase 22; Ubiquitin thiolesterase 22; ubiquitin-specific processing protease 22; Ubiquitin-specific-processing protease 22; USP22; USP3L
Gene ID : 23326
mRNA Refseq : NM_015276
Protein Refseq : NP_056091
MIM : 612116
UniProt ID : Q9UPT9
Chromosome Location : 17p11.2
Pathway : Chromatin modifying enzymes, organism-specific biosystem (from REACTOME); Chromatin organization, organism-specific biosystem (from REACTOME); Deubiquitination, organism-specific biosystem (from REACTOME)
Function : contributes_to H4 histone acetyltransferase activity; enzyme binding; ligand-dependent nuclear receptor transcription coactivator activity; protein binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.



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