Active Recombinant Human IL8

• Cat.No.: IL8-362H
• Product Overview: Human IL8 (P10145) full-elngth recombinant protein expressed in Escherichia coli.

Specification

• Cat. No.: IL8-362H
• Description: Interleukin-8 (IL8) is a chemokine produced by macrophages and other cell types such as epithelial cells. It is also synthesized by endothelial cells, which store IL8 in their storage vesicles, the Weibel-Palade bodies. In humans, the interleukin-8 protein is encoded by the IL8 gene.
• Theoretical MW (kDa): 8.4
• Form: Lyophilized
• Preparation Method: Escherichia coli expression system
• Purity: μ 98% by SDS-PAGE, μ 98% by HPLC
• Endotoxin Level: < 0.1 ng/ug
• Activity: The ED50 as determined by its chemotaxis of hCXCR2 transfected mouse BaF/3 cells is less than 0.5 ng/mL, corresponding to a specific activity of 2.0 x 106 units/mg.
• Application: SDS-PAGE
• Storage Buffer: Lyophilized from 20 mM PBS, 50 mM NaCl, pH 7.4
• Storage: Store at -20°C on dry atmosphere. After reconstitution with deionized water, store at -20°C. Aliquot to avoid repeated freezing and thawing.
• Unitprot ID: P10145

Gene Information

• Gene Name: IL8 interleukin 8 [ Homo sapiens ]
• Official Symbol: IL8
• Synonyms: IL8; 3-10C; AMCF-I; CXCL8; Emoctakin; GCP-1; GCP1; IL-8; K60; LECT; LUCT; LYNAP; MDNCF; MONAP; NAF; NAP-1; NAP1; SCYB8; TSG-1; b-ENAP; emoctakin; C-X-C motif chemokine 8; Granulocyte chemotactic protein 1; Monocyte-derived neutrophil chemotactic factor; Monocyte-derived neutrophil-activating peptide; Neutrophil-activating protein 1; Protein 3-10C; T cell chemotactic factor; T-cell chemotactic factor; beta-thromboglobulin-like protein; chemokine (C-X-C motif) ligand 8; interleukin 8; lymphocyte-derived neutrophil-activating factor; neutrophil-activating peptide 1; small inducible cytokine subfamily B, member 8; Interleukin-8
• Gene ID: 3576
• mRNA Refseq: NM_000584
• Protein Refseq: NP_000575
• MIM: 146930
• Chromosome Location: 4q13-q21
• Pathway: Cytokine-cytokine receptor interaction; Epithelial cell signaling in Helicobacter pylori infection; Leukocyte transendothelial migration; Toll-like receptor signaling pathway; Signaling by GPCR
• Function: chemokine activity; interleukin-8 receptor binding; protein binding