Active Recombinant Human Matrilin 3, His-tagged

Cat.No. : MATN3-5685H
Product Overview : Recombinant Human MATN3protein was expressed in Murine myeloma cell line with a C-terminal 6-Histag. Asp29-Arg486.
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Cat. No. : MATN3-5685H
Description : MATN3 is a 50-60 kDaextracellular matrix protein that belongs to the superfamily of vonWillebrand Factor A containing proteins. It is primarily expressed incartilage and functions as a bridging component between proteins of thecollagenous matrix. The human MATN3 cDNA encodes a 486 amino acid (aa)precursor with a 28 aa signal sequence, an N-terminal VWA domain, four tandemEGF-like repeats, and a C-terminal coiled coil domain. The Matrilins differin the number of VWA domains and EGF-like repeats they contain. Human MATN3 shares82% aa sequence identity with mouse MATN3.
Source : Mammalian cells
Form : Lyophilized from a0.2 μm filtered solution in PBS.
N-terminalSequence : Asp29
Molecular Weight : 50.6 kDa
Activity : Measuredby its binding ability in a functional ELISA. Immobilized rhCOMP at 2 μg/mL(100 μL/well) can bind rhMATN3 with alinear range of 1.5-100 ng/mL.
Endotoxin Level : <1.0 EUper 1 μg of the protein by the LAL method.
SDS-PAGE : 57 kDa,reducing conditions.
Purity : >95%,by SDS-PAGE under reducing conditions and visualized by silver stain.
Reconstitution : 100μg/mL in sterile PBS
Storage : Use amanual defrost freezer and avoid repeated freeze-thaw cycles. 12 months fromdate of receipt, -20 to -70°C as supplied. 1 month, 2 to 8°C under sterileconditions after reconstitution. 3 months, -20 to -70°C under sterileconditions after reconstitution.
Gene Name : MATN3 matrilin 3 [ Homosapiens ]
Official Symbol : MATN3
Synonyms : MATN3; matrilin 3; HOA;OS2; EDM5; DIPOA; OADIP; matrilin-3; OTTHUMP00000200547
Gene ID : 4148
mRNA Refseq : NM_002381
Protein Refseq : NP_002372
MIM : 602109
UniProt ID : O15232
Chromosome Location : 2p24-p23
Function : calcium ion binding;extracellular matrix structural constituent; protein binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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