Active Recombinant Human TNFRSF17(Met 1- Ala 54), Fc/His tagged
Cat.No. : | TNFRSF17-2348H |
Product Overview : | Recombinant Human TNFRSF17(Met 1- Ala 54)(NP_001183.2) was expressed in HEK293, fused with a polyhistidine-tagged Fc region of human IgG1 at the C-terminus and a signal peptide at the N-terminus. |
Availability | June 30, 2025 |
Unit | |
Price | |
Qty |
- Specification
- Gene Information
- Related Products
- Citation
- Download
Species : | Human |
Source : | HEK293 |
Tag : | Fc&His |
Protein Length : | Met 1- Ala 54 |
Form : | Liquid in sterile PBS, pH7.4. |
Bio-activity : | Measured by its binding ability in a functional ELISA. Immobilized recombinant human BAFF at 1 μg/ml (100 μl/well) can bind human TNFRSF17. The EC50 of human TNFRSF17 is 0.0059 μg/ml. |
Molecular Mass : | The recombinant human TNFRSF17/Fc is a disulfide-linked homodimer. The reduced monomer comprises 302 amino acids after removal of the signal peptide and has a predicted molecular mass of 34 kDa. |
Endotoxin : | <1EU/ug by LAL method. |
Purity : | Greater than 95% as determined by reducing SDS-PAGE. |
Storage : | Store it under sterile conditions at -20°C ~-70°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
Gene Name | TNFRSF17 TNF receptor superfamily member 17 [ Homo sapiens (human) ] |
Official Symbol | TNFRSF17 |
Synonyms | BCM; BCMA; CD269; TNFRSF13A; B cell maturation antigen; B-cell maturation factor; B-cell maturation protein |
Gene ID | 608 |
mRNA Refseq | NM_001192 |
Protein Refseq | NP_001183 |
UniProt ID | Q02223 |
◆ Recombinant Proteins | ||
TNFRSF17-1221H | Recombinant Human TNFRSF17 protein, His&Myc-tagged | +Inquiry |
TNFRSF17-04H | Active Recombinant Human TNFRSF17 Protein, Fc-tagged, Atto 647N conjugated | +Inquiry |
Tnfrsf17-661MAF647 | Active Recombinant Mouse Tnfrsf17 Protein, Fc-tagged, Alexa Fluor 647 conjugated | +Inquiry |
TNFRSF17-2922R | Active Recombinant Rabbit TNFRSF17 protein, His-tagged | +Inquiry |
Tnfrsf17-2266MAF488 | Recombinant Mouse Tnfrsf17 Protein, Fc/His-tagged, Alexa Fluor 488 conjugated | +Inquiry |
◆ Cell & Tissue Lysates | ||
TNFRSF17-2593MCL | Recombinant Mouse TNFRSF17 cell lysate | +Inquiry |
TNFRSF17-2489HCL | Recombinant Human TNFRSF17 cell lysate | +Inquiry |
TNFRSF17-1253CCL | Recombinant Cynomolgus TNFRSF17 cell lysate | +Inquiry |
TNFRSF17-1489RCL | Recombinant Rat TNFRSF17 cell lysate | +Inquiry |
Preclinical evaluation of CD8+ anti-BCMA mRNA CAR T-cells for treatment of multiple myeloma
Journal: Leukemia PubMed ID: 32632095 Data: 2020/6/26
Authors: Liang Lin, Shih-Feng Cho, Yu-Tzu Tai
Article Snippet:Viability of Descartes-08 cells was assessed using Acridine Orange and Propidium Iodide staining on the K2 Cellometer (Nexcelom Biosciences).Viability of Descartes-08 cells was assessed using Acridine Orange and Propidium Iodide staining on the K2 Cellometer (Nexcelom Biosciences).. CAR expression was determined by incubating CAR T-cells with 0.4 μg/ml of PE-conjugated recombinant BCMA (Recombinant human BCMA/TNFRSF17 protein, Fc/His-tagged, R-PE labeled; Creative BioMart, Shirley, NY) for 20 minutes at room temperature in FACS Buffer (DPBS, 0.5% BSA, 0.01% Sodium Azide).. Propidium Iodide was added at 1 μg/ml to stain non-viable cells.Propidium Iodide was added at 1 μg/ml to stain non-viable cells.

a Schematic representation of in vitro transcribed mRNA

NSG mice receiving MM1S-luc cells (2 × 10 6 cells per mouse i.v.) at day 0 were randomized into treatment groups (n=4 per group) on day 6. On days 7, 14, 21 and 28, T-cells were thawed from cryovials, washed, and resuspended for administration via i.v. injection with vehicle, 20 × 10 6 mock-transfected control TCR knockout (KO) CD8+ (ctrl CD8+) or Descartes-08 cells (showing 67%
Not For Human Consumption!
Inquiry
- Reviews (0)
- Q&As (0)
Ask a Question for All TNFRSF17 Products
Required fields are marked with *
My Review for All TNFRSF17 Products
Required fields are marked with *