Active Recombinant Human UBE2K Protein, His-tagged
Cat.No. : | UBE2K-649H |
Product Overview : | Recombinant Human UBE2K fused with His tag at N-terminal was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | UBE2K also known as UBC1 or ubiquitin-conjugating enzyme E2K belongs to the ubiquitin-conjugating enzyme family which interacts with RING finger proteins. UBE2K can ubiquitinate huntingtin, the gene product for Huntington's disease. Huntingtin is ubiquitinated in peripheral cells, suggesting a role for UBE2K in the degradation of huntingtin. UBE2K plays a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases. UBE2K also plays a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | 50mM sodium phosphate, pH 7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.25mM DTT, 25% glycerol. |
Bio-activity : | 11 nmol/min/mg |
Molecular Mass : | 26 kDa |
Purity : | >95% |
Applications : | Ubiquitin Enzyme Assay, Western Blot |
Stability : | 1 year at - 70 centigrade from the date of shipment. |
Storage : | Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Concentration : | 0.1 ug/ml |
Gene Name : | UBE2K ubiquitin-conjugating enzyme E2K [ Homo sapiens ] |
Official Symbol : | UBE2K |
Synonyms : | UBE2K; ubiquitin-conjugating enzyme E2K; HIP2, huntingtin interacting protein 2 , ubiquitin conjugating enzyme E2K (UBC1 homolog, yeast); ubiquitin-conjugating enzyme E2 K; HYPG; UBC1; HIP-2; E2(25K); ubiquitin-protein ligase; ubiquitin carrier protein; huntingtin interacting protein 2; huntingtin-interacting protein 2; ubiquitin-conjugating enzyme E2-25K; ubiquitin-conjugating enzyme E2(25K); ubiquitin-conjugating enzyme E2-25 KDA; ubiquitin-conjugating enzyme E2K (UBC1 homolog, yeast); LIG; HIP2; E2-25K; DKFZp564C1216; DKFZp686J24237; |
Gene ID : | 3093 |
mRNA Refseq : | NM_005339 |
Protein Refseq : | NP_005330 |
MIM : | 602846 |
UniProt ID : | P61086 |
Products Types
◆ Recombinant Protein | ||
Ube2k-6791M | Recombinant Mouse Ube2k Protein, Myc/DDK-tagged | +Inquiry |
UBE2K-0044H | Recombinant Human UBE2K Protein (A2-N200), Tag Free | +Inquiry |
UBE2K-4876R | Recombinant Rhesus Macaque UBE2K Protein, His (Fc)-Avi-tagged | +Inquiry |
UBE2K-9831M | Recombinant Mouse UBE2K Protein, His (Fc)-Avi-tagged | +Inquiry |
UBE2K-4758H | Recombinant Human UBE2K Protein, GST-tagged | +Inquiry |
◆ Lysates | ||
UBE2K-571HCL | Recombinant Human UBE2K 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket