ADP/ATP Ratio Assay Kit

Cat.No. : Kit-0058
Product Overview : ADP/ATP Ratio Assay Kit is a bioluminescent assay for ADP/ATP ratio.
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Applications : Apoptosis and Necrosis determination in cells.Cell proliferation: effects of cytokines, growth factor, nutrients.Drug discovery: high-throughput screening for anticancer drugs.
Storage : Store all reagents at -20°C. Shelf life: 12 months after receipt.

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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How are ATP proteins used in medical treatments? 05/02/2022

Various pharmacological agents that target ATP proteins are used in medical treatments. For example, drugs that inhibit the activity of ATP-dependent enzymes, such as ATPase or ATP citrate lyase, are used to treat various medical conditions, including hypertension, angina, and hyperlipidemia. Other drugs, such as proton pump inhibitors, work by inhibiting the H+/K+-ATPase enzyme in the stomach, thereby reducing acid production.

Are there any current clinical trials investigating ATP protein therapies? 10/24/2021

Yes, there are several clinical trials investigating ATP protein therapies. For example, a phase II clinical trial is evaluating the safety and efficacy of a drug called NVX-508, which targets ATP and activates the innate immune system to fight cancer. Another phase II clinical trial is testing the use of a drug called J147, which increases ATP levels in the brain and has potential therapeutic effects on Alzheimer's disease. Additionally, many ongoing clinical trials are investigating the use of ATP agonists and ATPase inhibitors in the treatment of various medical conditions.

Are there any risks or side effects associated with ATP protein therapies? 06/10/2021

Yes, like any other drug, ATP protein therapies may have risks and side effects. For example, drugs that target ATPase enzymes, such as verapamil and diltiazem, can cause side effects like constipation, headache, and dizziness. In addition, ATP agonists, such as adenosine, can cause side effects like facial flushing, chest pain, and low blood pressure. It is important for patients to discuss the potential risks and benefits of any treatment with their healthcare provider before starting therapy.

What are ATP proteins and how do they function in the body? 01/12/2021

ATP (adenosine triphosphate) proteins are a group of proteins that play a critical role in cellular metabolism and energy transfer throughout the body. ATP is a molecule that stores energy in its high-energy phosphate bonds, which can be broken to release energy for various cellular processes. ATP proteins facilitate the transfer of energy by catalyzing the transfer of phosphate groups onto ATP molecules, thus replenishing their energy stores.

Can ATP protein measurements be used as diagnostic or prognostic markers? 01/12/2021

Yes, measurements of ATP proteins, such as ATP levels in blood, can be used as diagnostic or prognostic markers in various medical conditions. For example, low ATP levels in muscle tissues or blood are associated with mitochondrial disorders. Additionally, abnormal ATP levels have been observed in various neurological disorders, including Alzheimer's disease, Parkinson's disease, and epilepsy. These measurements can help in the diagnosis of these conditions and in monitoring disease progression and treatment response.

What medical conditions are associated with ATP protein dysfunction? 10/29/2020

Dysfunction or abnormal activity of ATP proteins can lead to various medical conditions. For example, mutations in genes that code for ATP proteins can cause various genetic disorders, such as congenital myasthenic syndromes, which result in muscle weakness and fatigue. Dysfunction of ATP proteins in mitochondria, responsible for production of ATP, is associated with several metabolic disorders, including mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) syndrome.

How does ATP production occur in the cells? 09/06/2020

ATP production occurs through a process called cellular respiration, which occurs in the mitochondria of eukaryotic cells. The process involves the breakdown of glucose and other molecules, typically in the presence of oxygen, to generate energy that is used to produce ATP. There are three main stages of cellular respiration: glycolysis, the citric acid cycle, and oxidative phosphorylation. During glycolysis, glucose is broken down into pyruvate and a small amount of ATP is produced. The pyruvate then enters the citric acid cycle, where it is further broken down and more ATP is produced. Finally, oxidative phosphorylation occurs, where ATP is generated by the transfer of electrons along an electron transport chain.

How do ATP proteins play a role in cellular signaling and communication? 05/20/2020

ATP proteins are also involved in cellular signaling and communication. For example, ATP is released from injured tissues and cells and acts as a signaling molecule that activates purinergic receptors on immune cells, leading to an inflammatory response. ATP also acts as a neurotransmitter in the nervous system and is involved in synaptic transmission, synaptic plasticity, and cognitive functions.

What future developments can be expected in ATP protein research? 08/14/2019

Future developments in ATP protein research may include the identification of new targets for drug development, the development of new therapies for various medical conditions, and the refinement of diagnostic and prognostic tools. Additionally, a better understanding of the role of ATP proteins in cellular signaling and communication may lead to the development of new therapies for neurological and inflammatory disorders. Furthermore, advancements in technology, such as the use of CRISPR-Cas gene editing, may enable researchers to modify ATP protein activity and function, opening up new avenues for research.

How can ATP protein research lead to the development of new treatments? 04/27/2017

Studying ATP proteins and their functions can reveal new targets for drug development in various medical conditions, including metabolic disorders, cancer, and neurological diseases. Designing drugs that specifically target ATP proteins or affect their activity can lead to new effective treatments. Additionally, understanding the role of ATP proteins in cellular signaling and communication can lead to the development of novel therapies for various inflammatory and neurological disorders.

Customer Reviews (4)

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09/04/2020

    The customer support team has been very accommodating and responsive in addressing my concerns and ensuring my satisfaction with the product.

    06/13/2020

      The protein supplied is of exceptional quality and will perfectly fulfill the requirements for my intended experiments.

      11/05/2019

        I am thoroughly impressed with the quality of the protein and the exceptional customer service provided by the manufacturer.

        04/01/2019

          Their assistance has been invaluable in achieving successful outcomes.

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