AGE-RAGE in vitro Binding Assay Kit
|Product Overview :
|The AGE-RAGE in vitro Binding Assay Kit is primarily designed to screening inhibitors of AGE2 (glyceraldehyde-modified AGE)-sRAGE interaction (soluble RAGE) in vitro. In addition, this kit can be used for the rapid and sensitive evaluation of inhibitor candidates as well as characterization of AGE2-sRAGE interaction in vitro. The recombinant sRAGE used in this assay kit was specially designed for keeping the correct conformation to bind efficiently to AGE2-BSA but not to BSA, which are immobilized on the microplate surface. This technique allows us measuring the interaction of recombinant sRAGE to AGE2-BSA in a solid-phase assay system such as a conventional ELISA system.
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|1) Screening inhibitors of AGE-sRAGE interaction in vitro.
2) Characterization of inhibitor candidates of AGE2-sRAGE interaction in vitro.
3) Screening monoclonal antibodies that inhibit AGE2-sRAGE interaction in vitro.
4) Characterization of AGE2-sRAGE interaction in vitro.
|Upon receipt, store all other components at 4°C;
Don't expose reagents to excessive light.
All of the reagents included in the Research Product AGE-RAGE in vitro Binding Assay Kit have been tested for stability. Reagents should not be used beyond the stated expiration date.
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Q&As (20)Ask a question
AGE-RAGE signaling contributes to inflammation, oxidative stress, tissue damage, and disease progression.
AGE-RAGE interaction affects bone metabolism and can impact conditions like osteoporosis.
Scientists explore compounds to block or modulate AGE-RAGE interaction as potential therapies.
AGE-RAGE contributes to skin aging through oxidative stress and collagen damage.
The interaction is implicated in aging, diabetes, and age-related diseases, contributing to their pathology.
AGE-RAGE interaction contributes to complications in diabetes, promoting inflammation and tissue damage.
AGE-RAGE levels hold potential as biomarkers for diseases like diabetes and related complications.
Consuming a low-AGE diet may help reduce AGE-RAGE activation and its negative consequences.
AGE-RAGE interaction is implicated in lung diseases and inflammation, such as chronic obstructive pulmonary disease.
Scientists explore compounds to mitigate the effects of AGE-RAGE activation for potential therapies.
AGE-RAGE interaction is linked to neuroinflammation, influencing the progression of neurodegeneration.
AGEs bind to RAGE, activating signaling pathways that contribute to inflammation and oxidative stress.
Yes, ongoing research seeks to uncover new insights and therapeutic approaches related to AGE-RAGE.
AGE-RAGE activation can impair wound healing due to inflammation and oxidative stress.
Research delves into how AGE-RAGE signaling influences disease development and potential interventions.
Yes, AGE-RAGE signaling modulates immune cell functions and affects overall immune responses.
AGE-RAGE interaction contributes to diabetic nephropathy and kidney dysfunction.
Research investigates how AGE-RAGE activation influences cellular responses and disease progression.
AGE-RAGE activation contributes to cardiovascular diseases, including atherosclerosis.
AGE-RAGE activation triggers signaling cascades that lead to inflammation, oxidative stress, and tissue damage.
Customer Reviews (5)Write a review
The consistent results with Protein AGE-RAGE increased our experimental confidence.
Using this product, we obtained pure and reproducible protein complexes.
The product’s quality was evident in the absence of background noise in our assays.
Protein Q enabled accurate quantification of target proteins in western blots.
Dependable protein-protein interaction outcomes were achieved due to the product’s pure composition.
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