|Product Overview:||Recombinant Human CD-2 protein 25-209 a.a. expressed in E.coli,46 kDa.|
|Description:||CD2 which is also known as E-rosette receptor, T11 and lymphocytefunction antigen-2 (LFA-2) is expressed on T cells, thymocytes, and subset of natural killer cells. Human CD2 functions as the receptor for sheep erythrocytes, human CD58 (LFA-3), and CD15s (Sialyl Lewis X). p56lck, p59fyn, CD3eta and CD3epsilon are tyrosine-phosphorylated after CD2 stimulation. CD2 plays a role in T cell activation, T- or NK-cell-mediated cytolysis, apoptosis in activated peripheral T cells, and regulation of T cell anergy.|
|Synonyms:||CD2; SRBC; T11; LFA-2; OTTHUMP00000024366; OTTHUMP00000059318; CD2 antigen; CD2 antigen (p50), sheep red blood cell receptor; CD2 molecule; Erythrocyte receptor; LFA-3 receptor; Rosette receptor; T-cell surface antigen T11/Leu-5; lymphocyte-function antigen-2; FLJ46032.|
|Presentation:||Recombinant Human CD-2 protein at 100µg/ml in 50mM Tris-Acetate, pH7.5, 1mM EDTA and 20% Glycerol.|
|Applications:||•ELISA•Inhibition Assays •Western Blotting|
|Characterization:||On SDS-PAGE commassie blue stained gel, the purified recombinant protein shows a band at 46 kDa.|
|Storage:||Store vial at -200C to -800C. When stored at the recommended temperature, this protein is stable for 12 months.|
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