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Recombinant Human NAMPT, His-tagged

Cat.No. : NAMPT-311H
Product Overview : Recombinant Human NAMPT(aa 1-491) ) fused a His-tag at the C-terminus was expressed in E. coli.
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  • Gene Information
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Cat. No. : NAMPT-311H
Description : This gene encodes a protein that catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. The protein belongs to the nicotinic acid phosphoribosyltransferase (NAPRTase) family and is thought to be involved in many important biological processes, including metabolism, stress response and aging. This gene has a pseudogene on chromosome 10.
Source : E. coli
Molecular Mass : ~52kDa
Formulation : Lyophilized. Salt-free.
Purity : ≥90% as determined by SDS­PAGE
Endotoxin Content : <1EU/μg purified protein (LAL test; Lonza).
Concentration : 0.05 mg/ml
Reconstitution : Reconstitute in distilled water.
Storage : Working aliquots are stable for up to 3 months when stored at -20°C.
OfficialSymbol : NAMPT
Gene Name : NAMPT nicotinamide phosphoribosyltransferase [ Homo sapiens ]
Synonyms : NAMPT; nicotinamide phosphoribosyltransferase; PBEF1, pre B cell colony enhancing factor 1; PBEF; visfatin
Gene ID : 10135
mRNA Refseq : NM_005746
Protein Refseq : NP_005737
MIM : 608764
UniProt ID : P43490
Chromosome Location : 7q22.3
Pathway : Adipogenesis; Metabolism; Metabolism of vitamins and cofactors; Metabolism of water-soluble vitamins and cofactors; Nicotinamide salvaging
Function : cytokine activity; nicotinamide phosphoribosyltransferase activity; nicotinate phosphoribosyltransferase activity; nicotinate-nucleotide diphosphorylase (carboxylating) activity; transferase activity, transferring glycosyl groups

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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What are the mutation types of NAMPT? 11/19/2022

The types of mutations in NAMPT include point mutations, insertions/deletions, duplications, etc., which can cause structural and functional abnormalities of the protein.

How can diseases be treated by regulating NAMPT levels? 08/31/2022

Some diseases related to NAD+ metabolism can be treated by regulating the level of NAMPT, such as by inhibiting its activity or regulating its expression.

How to study the regulatory mechanism of NAMPT? 08/05/2022

Studying the regulatory mechanism of NAMPT requires a comprehensive use of various experimental methods and techniques, such as gene knockout, transcriptome analysis, and protein-protein interactions.

What is the relationship of NAMPT to other genes or proteins? 07/04/2022

NAMPT has a complex relationship with other genes or proteins, and can interact with other genes or proteins and participate in a variety of biochemical reactions.

What is the specific role of NAMPT in cellular energy metabolism? 03/21/2022

NAMPT plays an important role in cellular energy metabolism by catalyzing the synthesis of NAD+, an important intracellular coenzyme involved in various reactions of energy metabolism.

How are mutations in NAMPT detected and analyzed? 12/01/2019

Mutations in NAMPT can be detected and analyzed by methods such as whole-genome sequencing or target region sequencing to understand the impact of mutations on protein structure and function.

Customer Reviews (3)

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Reviews
06/24/2022

    Does not trigger an immune response.

    12/14/2021

      Methods such as ELISA or immunostaining perform well.

      11/13/2021

        Easy to use, high stability, remarkable effect.

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