Recombinant Human NAMPT, His-tagged
Cat.No. : | NAMPT-311H |
Product Overview : | Recombinant Human NAMPT(aa 1-491) ) fused a His-tag at the C-terminus was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Cat. No. : | NAMPT-311H |
Description : | This gene encodes a protein that catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. The protein belongs to the nicotinic acid phosphoribosyltransferase (NAPRTase) family and is thought to be involved in many important biological processes, including metabolism, stress response and aging. This gene has a pseudogene on chromosome 10. |
Source : | E. coli |
Molecular Mass : | ~52kDa |
Formulation : | Lyophilized. Salt-free. |
Purity : | ≥90% as determined by SDSPAGE |
Endotoxin Content : | <1EU/μg purified protein (LAL test; Lonza). |
Concentration : | 0.05 mg/ml |
Reconstitution : | Reconstitute in distilled water. |
Storage : | Working aliquots are stable for up to 3 months when stored at -20°C. |
OfficialSymbol : | NAMPT |
Gene Name : | NAMPT nicotinamide phosphoribosyltransferase [ Homo sapiens ] |
Synonyms : | NAMPT; nicotinamide phosphoribosyltransferase; PBEF1, pre B cell colony enhancing factor 1; PBEF; visfatin |
Gene ID : | 10135 |
mRNA Refseq : | NM_005746 |
Protein Refseq : | NP_005737 |
MIM : | 608764 |
UniProt ID : | P43490 |
Chromosome Location : | 7q22.3 |
Pathway : | Adipogenesis; Metabolism; Metabolism of vitamins and cofactors; Metabolism of water-soluble vitamins and cofactors; Nicotinamide salvaging |
Function : | cytokine activity; nicotinamide phosphoribosyltransferase activity; nicotinate phosphoribosyltransferase activity; nicotinate-nucleotide diphosphorylase (carboxylating) activity; transferase activity, transferring glycosyl groups |
Products Types
◆ Recombinant Protein | ||
NAMPT-2531H | Recombinant Human NAMPT protein(Met1-His491), His&GST-tagged | +Inquiry |
NAMPT-3554R | Recombinant Rat NAMPT Protein, His (Fc)-Avi-tagged | +Inquiry |
NAMPT-01H | Active Recombinant Human NAMPT Protein, His-tagged | +Inquiry |
NAMPT-3579H | Recombinant Human NAMPT Protein, His (Fc)-Avi-tagged | +Inquiry |
Nampt-383M | Recombinant Mouse Nampt Protein, His-tagged | +Inquiry |
◆ Lysates | ||
NAMPT-491HCL | Recombinant Human NAMPT cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionThe types of mutations in NAMPT include point mutations, insertions/deletions, duplications, etc., which can cause structural and functional abnormalities of the protein.
Some diseases related to NAD+ metabolism can be treated by regulating the level of NAMPT, such as by inhibiting its activity or regulating its expression.
Studying the regulatory mechanism of NAMPT requires a comprehensive use of various experimental methods and techniques, such as gene knockout, transcriptome analysis, and protein-protein interactions.
NAMPT has a complex relationship with other genes or proteins, and can interact with other genes or proteins and participate in a variety of biochemical reactions.
NAMPT plays an important role in cellular energy metabolism by catalyzing the synthesis of NAD+, an important intracellular coenzyme involved in various reactions of energy metabolism.
Mutations in NAMPT can be detected and analyzed by methods such as whole-genome sequencing or target region sequencing to understand the impact of mutations on protein structure and function.
Customer Reviews (3)
Write a reviewDoes not trigger an immune response.
Methods such as ELISA or immunostaining perform well.
Easy to use, high stability, remarkable effect.
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