Recombinant Human Coagulation Factor C Homolog, Cochlin (Limulus Polyphemus) COCH-3899H

Recombinant Human Coagulation Factor C Homolog, Cochlin (Limulus Polyphemus)

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Recombinant Human Coagulation Factor C Homolog, Cochlin (Limulus Polyphemus)

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Cat. No. : COCH-3899H
Product Overview : A DNA sequence encoding the mature form of human COCH (NP_001128530.1) (Glu 25-Gln 550) was expressed, with a polyhistidine tag at the N-terminus.
Description : COCH, is a secreted protein which contains one LCCL domain and two VWFA domains. Cochlin / COCH is an abundant inner ear protein expressed as multiple isoforms. Its function is also unknown, but it is suspected to be an extracellular matrix component. Cochlin / COCH and type II collagen are major constituents of the inner ear extracellular matrix, and COCH constitutes 70% of non-collagenous protein in the inner ear and the expression is highly specific.
Source : Human
Host : Human Cells
Form : Lyophilized from sterile PBS, pH 7.4.
Purity : > 92 % as determined by SDS-PAGE
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method.
Stability : Samples are stable for up to twelve months from date of receipt at -70°C.
Predicted N terminal : His
Molecular Mass : The recombinant full length of human COCH consists of 542 amino acids and has a calculated molecular mass of 59.4 kDa. In SDS-PAGE under reducing conditions, rhCOCH migrates as three bands with apparent molecular mass of 66, 48 and 18 kDa, corresponding to the alternative splicing isoforms.
Application : SDS-PAGE
Reconstitution : A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information
Storage : Store it under sterile conditions at -70°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
PDBrendering based on 1jbi :

Gene Name : COCH coagulation factor C homolog, cochlin (Limulus polyphemus) [ Homo sapiens ]
Official Symbol : COCH
Synonyms : COCH; coagulation factor C homolog, cochlin (Limulus polyphemus); DFNA9; COCH5B2; COCH-5B2; cochlin; OTTHUMP00000178782
Gene ID : 1690
mRNA Refseq : NM_001135058
Protein Refseq : NP_001128530
MIM : 603196
UniProt ID : O43405
Chromosome Location : 14q11.2-q13

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