"HDAC10" Related Products


Recombinant Human Histone Deacetylase 10, GST-tagged

Cat. No.: HDAC10-1588H
Product Overview: Recombinant human HDAC10 (1-482) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Description: HDAC10 belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. HDAC10 belongs to class II of the histone deacetylase family that catalyzes the deacetylation of lysine residues in the N-terminal tail of histones and represses transcription in large multiprotein complexes with transcriptional co-repressors.
Applications: HDAC Assay, Western Blot
Molecular Weight: 77 kDa
Expression System: Sf9 insect cells using baculovirus
Species: Human
Form: Recombinant protein stored in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.
Purity: >80%
Concentration: 0.1 ug/ul
Specific Activity: 120 RLU/min/ng
Sequences: 1-482
Storage: Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Pathways: Signaling events mediated by HDAC Class I; NAD-dependent histone deacetylase activity (H3-K14 specific)
Gene Name: HDAC10 histone deacetylase 10 [ Homo sapiens ]
Official Symbol: HDAC10
Synonyms: HDAC10; histone deacetylase 10; HD10; MGC149722; DKFZp761B039; histone deacetylase 10; OTTHUMP00000042162; OTTHUMP00000196674; OTTHUMP00000196675; OTTHUMP00000197621
Gene ID: 83933
mRNA Refseq: NM_032019
Protein Refseq: NP_114408
MIM: 608544
UniProt ID: Q969S8
Chromosome Location: 22q13
Function: NAD-dependent histone deacetylase activity (H3-K14 specific); NAD-dependent histone deacetylase activity (H3-K9 specific); NAD-dependent histone deacetylase activity (H4-K16 specific); enzyme binding; histone deacetylase activity; histone deacetylase activity (H3-K16 specific); histone deacetylase binding; hydrolase activity; protein binding; protein deacetylase activity

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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