"HDAC10" Related Products

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Recombinant Human Histone Deacetylase 10, GST-tagged

Cat. No. : HDAC10-1588H
Product Overview : Recombinant human HDAC10 (1-482) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Description : HDAC10 belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. HDAC10 belongs to class II of the histone deacetylase family that catalyzes the deacetylation of lysine residues in the N-terminal tail of histones and represses transcription in large multiprotein complexes with transcriptional co-repressors.
Applications : HDAC Assay, Western Blot
Molecular Weight : 77 kDa
Expression System : Sf9 insect cells using baculovirus
Species : Human
Form : Recombinant protein stored in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.
Purity : >80%
Concentration : 0.1 ug/ul
Specific Activity : 120 RLU/min/ng
Sequences : 1-482
Storage : Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Pathways : Signaling events mediated by HDAC Class I; NAD-dependent histone deacetylase activity (H3-K14 specific)
Gene Name : HDAC10 histone deacetylase 10 [ Homo sapiens ]
Official Symbol : HDAC10
Synonyms : HDAC10; histone deacetylase 10; HD10; MGC149722; DKFZp761B039; histone deacetylase 10; OTTHUMP00000042162; OTTHUMP00000196674; OTTHUMP00000196675; OTTHUMP00000197621
Gene ID : 83933
mRNA Refseq : NM_032019
Protein Refseq : NP_114408
MIM : 608544
UniProt ID : Q969S8
Chromosome Location : 22q13
Function : NAD-dependent histone deacetylase activity (H3-K14 specific); NAD-dependent histone deacetylase activity (H3-K9 specific); NAD-dependent histone deacetylase activity (H4-K16 specific); enzyme binding; histone deacetylase activity; histone deacetylase activity (H3-K16 specific); histone deacetylase binding; hydrolase activity; protein binding; protein deacetylase activity

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