Recombinant Human COP1, His-tagged

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Recombinant Human COP1, His-tagged

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Cat.No. : COP1-11454H
Product Overview : Recombinant Human COP1 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.
Source : E.coli
Species : Human
Tag : His
Protein length : 381-731a.a.
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.
Gene Name : RFWD2 ring finger and WD repeat domain 2, E3 ubiquitin protein ligase [ Homo sapiens ]
Official Symbol : RFWD2
Synonyms : RFWD2; ring finger and WD repeat domain 2, E3 ubiquitin protein ligase; ring finger and WD repeat domain 2; E3 ubiquitin-protein ligase RFWD2; COP1; FLJ10416; RNF200; hCOP1; RING finger protein 200; putative ubiquitin ligase COP1; RING finger and WD repeat domain protein 2; constitutive photomorphogenic protein (COP1); constitutive photomorphogenesis protein 1 homolog; RP11-318C24.3;
Gene ID : 64326
mRNA Refseq : NM_001001740
Protein Refseq : NP_001001740
MIM : 608067
UniProt ID : Q8NHY2
Chromosome Location : 1q25.1-q25.2
Pathway : Autodegradation of the E3 ubiquitin ligase COP1, organism-specific biosystem; Cell Cycle, organism-specific biosystem; Cell Cycle Checkpoints, organism-specific biosystem; Direct p53 effectors, organism-specific biosystem; G1/S DNA Damage Checkpoints, organism-specific biosystem; Stabilization of p53, organism-specific biosystem; Ubiquitin mediated proteolysis, organism-specific biosystem;
Function : ligase activity; metal ion binding; protein binding; zinc ion binding;

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