Recombinant Human LIMK1, GST-tagged
Cat.No. : | LIMK1-131H |
Product Overview : | Recombinant human LIMK1 (285-638) was expressed by baculovirus in Sf9 cells using an N-terminal GST tag. |
- Specification
- Gene Information
- Related Products
Description : | LIMK1 or LIM domain kinase 1 contains a unique combination of 2 N-terminal LIM domain and a C-terminal protein kinase domain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers that can bind to DNA/RNA as well as mediating protein-protein interactions. LIMK1 is thought to be a component of an intracellular signaling pathway that may be involved in brain development especially development of nerve cells. LIMK1 may play an important role in areas of the brain that are responsible for processing visual-spatial information (visuospatial constructive cognition). LIMK1 can regulate aspects of the cytoskeleton, the structural framework that helps to determine cell shape, size, and movement. |
Source : | Sf9 insect cells using baculovirus |
Species : | Human |
Tag : | GST |
Form : | Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
Molecular Mass : | ~65 kDa |
Purity : | >95% by densitometry |
Applications : | Kinase Assay, Western Blot |
Storage : | Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Concentration : | 0.1 μg/μl |
Gene Name : | LIMK1 LIM domain kinase 1 [ Homo sapiens ] |
Official Symbol : | LIMK1 |
Synonyms : | LIMK1; LIM domain kinase 1; LIMK; LIM motif-containing protein kinase; LIMK-1; |
Gene ID : | 3984 |
mRNA Refseq : | NM_001204426 |
Protein Refseq : | NP_001191355 |
MIM : | 601329 |
UniProt ID : | P53667 |
Chromosome Location : | 7q11.23 |
Pathway : | Axon guidance, organism-specific biosystem; Axon guidance, conserved biosystem; Axon guidance, organism-specific biosystem; Axon guidance, organism-specific biosystem; CDC42 signaling events, organism-specific biosystem; CXCR4-mediated signaling events, organism-specific biosystem; Caspase cascade in apoptosis, organism-specific biosystem; |
Function : | ATP binding; heat shock protein binding; metal ion binding; nucleotide binding; protein binding; protein kinase activity; protein serine/threonine kinase activity; zinc ion binding; |
Products Types
◆ Recombinant Protein | ||
LIMK1-5085M | Recombinant Mouse LIMK1 Protein, His (Fc)-Avi-tagged | +Inquiry |
LIMK1-1177H | Recombinant Human LIMK1 Protein (R329-G638), His tagged | +Inquiry |
LIMK1-1176H | Recombinant Human LIMK1 Protein (R329-G638), Tag Free | +Inquiry |
LIMK1-39H | Recombinant Human LIMK1 Protein (285-638), N-GST tagged | +Inquiry |
Limk1-1320M | Recombinant Mouse Limk1 Protein, MYC/DDK-tagged | +Inquiry |
◆ Lysates | ||
LIMK1-4739HCL | Recombinant Human LIMK1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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