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Recombinant Human PKLR, His-tagged

Cat.No.: PKLR-364H
Product Overview: A DNA sequence encoding the human PKLR (NP_000289.1) (Leu47-Ser574) was expressed with a polyhistidine tag at the N-terminus.
Source: E. coli
Species: Human
Tag: His
Form: Lyophilized from sterile PBS, pH7.4.
Molecular Mass: The recombinant human PKLR consists of 546 amino acids and predicts a molecular mass of 59.1 KDa. It migrates as an approximately 53-60 KDa band in SDS-PAGE under reducing conditions.
Protein length: Leu47-Ser574
Endotoxin: < 1.0 eu per μg of the protein as determined by the LAL method.
Purity: >85 % as determined by SDS-PAGE
Stability: Samples are stable for up to twelve months from date of receipt at -70℃
Storage: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: Hardcopy of COA with reconstitution instruction is sent along with the products.
Gene Name: PKLR pyruvate kinase, liver and RBC [ Homo sapiens ]
Official Symbol: PKLR
Synonyms: PKLR; pyruvate kinase, liver and RBC; pyruvate kinase isozymes R/L; pyruvate kinase 1; pyruvate kinase type L; pyruvate kinase isozyme R/L; R-type/L-type pyruvate kinase; red cell/liver pyruvate kinase; pyruvate kinase, liver and blood cell; PK1; PKL; PKR; RPK; PKRL;
Gene ID: 5313
mRNA Refseq: NM_000298
Protein Refseq: NP_000289
MIM: 609712
UniProt ID: P30613
Chromosome Location: 1q22
Pathway: ChREBP activates metabolic gene expression, organism-specific biosystem; Developmental Biology, organism-specific biosystem; FOXA2 and FOXA3 transcription factor networks, organism-specific biosystem; Glucose metabolism, organism-specific biosystem; Glycolysis, organism-specific biosystem; Glycolysis / Gluconeogenesis, organism-specific biosystem; Glycolysis / Gluconeogenesis, conserved biosystem;
Function: ATP binding; magnesium ion binding; nucleotide binding; potassium ion binding; pyruvate kinase activity; transferase activity;

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