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Recombinant Rat Serpine1, Fc-tagged

Cat.No.: Serpine1-564R
Product Overview: A DNA sequence encoding the rat SERPINE1 (NP_036752.1) (Met1-Pro402) was expressed with the Fc region of human IgG1 at the C-terminus.
Source: Human Cells
Species: Rat
Tag: Fc
Form: Lyophilized from sterile PBS, pH7.4.
Bio-activity: Measured by its ability to inhibit uPA cleavage of a peptide substrate, N-carbobenzyloxy-Gly-Gly-Arg-7-amido-4-methylcoumarin (Z-GGR-AMC). The IC50 value is< 10>
Molecular Mass: The recombinant rat SERPINE1 comprises 620 amino acids and has a predicted molecular mass of 69.6 kDa. The apparent molecular mass of the protein is approximately 70 kDa in SDS-PAGE under reducing conditions.
Protein length: Met1-Pro402
Endotoxin: < 1.0 eu per μg of the protein as determined by the LAL method.
Purity: >90 % as determined by SDS-PAGE
Stability: Samples are stable for up to twelve months from date of receipt at -70℃
Storage: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: Hardcopy of COA with reconstitution instruction is sent along with the products.
Gene Name: Serpine1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 [ Rattus norvegicus ]
Official Symbol: Serpine1
Synonyms: SERPINE1; serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; plasminogen activator inhibitor 1; PAI; PAI-1; serpin E1; endothelial plasminogen activator inhibitor; serine (or cysteine) proteinase inhibitor, member 1; serine (or cysteine) peptidase inhibitor, clade E, member 1; serine (or cysteine) proteinase inhibitor, clade E, member 1; serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; Pai1; PAI1A; Planh; Pai1aa; RATPAI1A;
Gene ID: 24617
mRNA Refseq: NM_012620
Protein Refseq: NP_036752
Pathway: Adipogenesis, organism-specific biosystem; Blood Clotting Cascade, organism-specific biosystem; Chagas disease (American trypanosomiasis), organism-specific biosystem; Chagas disease (American trypanosomiasis), conserved biosystem; Complement and Coagulation Cascades, organism-specific biosystem; Complement and coagulation cascades, organism-specific biosystem; Complement and coagulation cascades, conserved biosystem;
Function: peptidase inhibitor activity; protease binding; protease binding; receptor binding; contributes_to receptor binding; serine-type endopeptidase inhibitor activity; serine-type endopeptidase inhibitor activity; serine-type endopeptidase inhibitor activity;

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