"CRKL" Related Products

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Recombinant Human CRKL cell lysate

Cat.No.: CRKL-403HCL
Description: This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic
Species: Human
Size: 100 ul
Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Applications: Western Blot;
Gene Name: CRKL v-crk sarcoma virus CT10 oncogene homolog (avian)-like [ Homo sapiens ]
Official Symbol: CRKL
Synonyms: CRKL; v-crk sarcoma virus CT10 oncogene homolog (avian)-like; v crk avian sarcoma virus CT10 oncogene homolog like; crk-like protein;
Gene ID: 1399
mRNA Refseq: NM_005207
Protein Refseq: NP_005198
MIM: 602007
UniProt ID: P46109
Chromosome Location: 22q11.21
Pathway: B Cell Receptor Signaling Pathway, organism-specific biosystem; Bacterial invasion of epithelial cells, organism-specific biosystem; Bacterial invasion of epithelial cells, conserved biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Chronic myeloid leukemia, organism-specific biosystem; Chronic myeloid leukemia, conserved biosystem;
Function: SH3/SH2 adaptor activity; protein binding; signal transducer activity;

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