Cat.No.: | LRR1-1398HCL |
Description: | The protein encoded by this gene contains a leucine-rich repeat (LRR). It specifically interacts with TNFRSF9/4-1BB, a member of the tumor necrosis factor receptor (TNFR) superfamily. Overexpression of this gene suppresses the activation of NF-kappa B induced by TNFRSF9 or TNF receptor-associated factor 2 (TRAF2), which suggests that this protein is a negative regulator of TNFRSF9-mediated signaling cascades. At least three alternatively spliced transcript variants encoding distinct isoforms have been observed. |
Species: | Human |
Size: | 100 ul |
Storage Buffer: | 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue) |
Applications: | Western Blot; |
Gene Name: | LRR1?leucine rich repeat protein 1 [?Homo sapiens?(human) ] |
Official Symbol: | LRR1 |
Synonyms: | LRR1; leucine rich repeat protein 1; LRR-1; PPIL5; 4-1BBLRR; leucine-rich repeat protein 1; cyclophilin-like 5; LRR-repeat protein 1; peptidylprolyl isomerase-like 5; 4-1BB-mediated signaling molecule; 4-1BB-mediated-signaling molecule; peptidylprolyl isomerase (cyclophilin)-like 5, isoform 3 |
Gene ID: | 122769 |
mRNA Refseq: | NM_152329 |
Protein Refseq: | NP_689542 |
MIM: | 609193 |
UniProt ID: | Q96L50 |
Chromosome Location: | 14q21.3 |
Pathway: | Adaptive Immune System, organism-specific biosystem; Antigen processing: Ubiquitination & Proteasome degradation, organism-specific biosystem; Class I MHC mediated antigen processing & presentation, organism-specific biosystem; Immune System, organism-specific biosystem |
Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.