Recombinant Human LRR1 cell lysate

• Cat.No.: LRR1-1398HCL

Specification

• Description: The protein encoded by this gene contains a leucine-rich repeat (LRR). It specifically interacts with TNFRSF9/4-1BB, a member of the tumor necrosis factor receptor (TNFR) superfamily. Overexpression of this gene suppresses the activation of NF-kappa B induced by TNFRSF9 or TNF receptor-associated factor 2 (TRAF2), which suggests that this protein is a negative regulator of TNFRSF9-mediated signaling cascades. At least three alternatively spliced transcript variants encoding distinct isoforms have been observed.
• Species: Human
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: LRR1?leucine rich repeat protein 1 [?Homo sapiens?(human) ]
• Official Symbol: LRR1
• Synonyms: LRR1; leucine rich repeat protein 1; LRR-1; PPIL5; 4-1BBLRR; leucine-rich repeat protein 1; cyclophilin-like 5; LRR-repeat protein 1; peptidylprolyl isomerase-like 5; 4-1BB-mediated signaling molecule; 4-1BB-mediated-signaling molecule; peptidylprolyl isomerase (cyclophilin)-like 5, isoform 3
• Gene ID: 122769
• mRNA Refseq: NM_152329
• Protein Refseq: NP_689542
• MIM: 609193
• UniProt ID: Q96L50
• Chromosome Location: 14q21.3
• Pathway: Adaptive Immune System, organism-specific biosystem; Antigen processing: Ubiquitination & Proteasome degradation, organism-specific biosystem; Class I MHC mediated antigen processing & presentation, organism-specific biosystem; Immune System, organism-specific biosystem