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Native Human Apotransferrin Protein

Cat.No. : TFRC-16H
  • Specification
  • Gene Information
  • Related Products
Source : Human plasma
Species : Human
Form : Lyophilized from 10 mM phosphate buffer, pH 7.4.
Purity : >95% pure by SDS-PAGE
Storage : Store at -20°C. Avoid freeze-thaw cycles.
Reconstitution : Deionized H2O.
Gene Name : TFRC transferrin receptor (p90, CD71) [ Homo sapiens ]
Official Symbol : TFRC
Synonyms : TFRC; transferrin receptor (p90, CD71); transferrin receptor protein 1; CD71; TFR1; T9; TR; TFR; p90; TRFR;
Gene ID : 7037
mRNA Refseq : NM_001128148
Protein Refseq : NP_001121620
MIM : 190010
UniProt ID : P02786
Chromosome Location : 3q26.2-qter
Pathway : Clathrin derived vesicle budding, organism-specific biosystem; Endocytosis, organism-specific biosystem; Endocytosis, conserved biosystem; FOXA2 and FOXA3 transcription factor networks, organism-specific biosystem; Golgi Associated Vesicle Biogenesis, organism-specific biosystem; HIF-1-alpha transcription factor network, organism-specific biosystem; Hematopoietic cell lineage, organism-specific biosystem;
Function : Hsp70 protein binding; chaperone binding; peptidase activity; receptor activity; transferrin receptor activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Can TFRC be used to develop targeted drug delivery systems? 09/13/2022

Yes, TFRC's presence on cell surfaces has been exploited for the development of targeted drug delivery systems, especially for delivering drugs to cancer cells.

Are there any therapies that target TFRC in cancer treatment? 11/17/2020

Yes, some experimental therapies aim to target TFRC on cancer cells, such as antibody-drug conjugates (ADCs) and small-molecule inhibitors.

Are there any clinical conditions associated with TFRC protein dysregulation? 09/19/2017

Yes, dysregulation of TFRC expression or function can be associated with various medical conditions, including anemia, cancer, and neurodegenerative diseases.

How is TFRC protein studied in clinical research and diagnostics? 10/03/2016

Researchers use techniques like immunohistochemistry and molecular assays to study TFRC expression levels in patient samples. This helps in diagnosis and prognosis.

How can TFRC be relevant in the treatment of iron-deficiency anemia? 01/02/2016

Understanding TFRC expression in the context of anemia can help identify the underlying causes and guide treatment strategies to improve iron uptake.

Customer Reviews (3)

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Reviews
09/06/2021

    In addition to the advantages of GAD1 protein itself, the manufacturer can play a crucial role in supporting the research efforts.

    04/19/2018

      This quality control is essential for obtaining reliable and reproducible data, as any variability in protein quality can introduce confounding factors into experiments.

      01/27/2017

        This versatility enables researchers to explore GAD1's function and role in a range of biological processes, making it a valuable tool across diverse research fields.

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