"MAOB" Related Products

Recombinant Human monoamine oxidase B,His-tagged

Cat. No. : MAOB-107H
Product Overview : Recombinant Human MAO-B comprises a 488 amino acid fragment (2-489) corresponding to the cytoplasmic domain fragment of the mature MAO-B protein and is expressed in E. coli with an amino-terminal hexahistidine tag.
Description : Monoamine oxidase B (MAO-B) is a flavin-containing mitochondrial enzyme, which catalyzes the oxidative deamination of biogenic and xenobiotic monoamines. It regulates the metabolic degradation of catecholamines and serotonin in neural and other target tissues. MAO-B is found platelets and in dopamine-secreting neurons in the brain. Increased levels of MAO B that have been identified in brain of Alzheimer's patients. Monoamine oxidases (MAO B and MAO A) are well-known targets for antidepressant drugs and for drugs used to treat neurological disorders and aging diseases, such as Parkinson's and Alzheimer's disease.
Source : E.coli.
Purity : >95% by SDS-PAGE
Form : Liquid
Storage : Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Please avoid freeze thaw cycles.
PDBrendering based on 1gos. Available structures:1gos,1oj9,1oja,1ojb,1ojc,1ojd,1s2q,1s2y,1s3b,1s3e,2bk3,2bk4,2bk5,2byb,2c64,2c65,2c66,2c67,2c70,2c72,2c73,2c75,2c76 :

Gene Name : MAOB monoamine oxidase B [ Homo sapiens ]
Synonyms : MAOB; MGC26382; monoamine oxidase B; MAO, brain; MAO, platelet; tyramine oxidase; adrenalin oxidase; EC 1.4.3.4; MAO-B.
Gene ID : 4129
mRNA Refseq : NM_000898
Protein Refseq : NP_000889
MIM : 309860
UniProt ID : P27338.3
Chromosome Location : Xp11.23
Pathway : Glycine, serine and threonine metabolism; Histidine metabolism; Phenylalanine metabolism; Tryptophan metabolism; Tyrosine metabolism; Urea cycle and metabolism of amino groups; Biological oxidations
Function : amine oxidase activity; electron carrier activity; oxidoreductase activity

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