"MAOB" Related Products

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Recombinant Human monoamine oxidase B,His-tagged

Cat. No.: MAOB-107H
Product Overview: Recombinant Human MAO-B comprises a 488 amino acid fragment (2-489) corresponding to the cytoplasmic domain fragment of the mature MAO-B protein and is expressed in E. coli with an amino-terminal hexahistidine tag.
Description: Monoamine oxidase B (MAO-B) is a flavin-containing mitochondrial enzyme, which catalyzes the oxidative deamination of biogenic and xenobiotic monoamines. It regulates the metabolic degradation of catecholamines and serotonin in neural and other target tissues. MAO-B is found platelets and in dopamine-secreting neurons in the brain. Increased levels of MAO B that have been identified in brain of Alzheimer's patients. Monoamine oxidases (MAO B and MAO A) are well-known targets for antidepressant drugs and for drugs used to treat neurological disorders and aging diseases, such as Parkinson's and Alzheimer's disease.
Source: E.coli.
Purity: >95% by SDS-PAGE
Form: Liquid
Storage: Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Please avoid freeze thaw cycles.
Gene Name: MAOB monoamine oxidase B [ Homo sapiens ]
Synonyms: MAOB; MGC26382; monoamine oxidase B; MAO, brain; MAO, platelet; tyramine oxidase; adrenalin oxidase; EC 1.4.3.4; MAO-B.
Gene ID: 4129
mRNA Refseq: NM_000898
Protein Refseq: NP_000889
MIM: 309860
UniProt ID: P27338.3
Chromosome Location: Xp11.23
Pathway: Glycine, serine and threonine metabolism; Histidine metabolism; Phenylalanine metabolism; Tryptophan metabolism; Tyrosine metabolism; Urea cycle and metabolism of amino groups; Biological oxidations
Function: amine oxidase activity; electron carrier activity; oxidoreductase activity

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