Recombinant Human PLK1 protein, MYC/DDK-tagged
Cat.No. : | PLK1-575H |
Product Overview : | Recombinant Human PLK1 fused with MYC/DDK tag at C-terminal was expressed in HEK293. |
- Specification
- Gene Information
- Related Products
Description : | The Ser/Thr protein kinase encoded by this gene belongs to the CDC5/Polo subfamily. It is highly expressed during mitosis and elevated levels are found in many different types of cancer. Depletion of this protein in cancer cells dramatically inhibited cell proliferation and induced apoptosis; hence, it is a target for cancer therapy. |
Source : | HEK293 |
Species : | Human |
Tag : | MYC/DDK |
Form : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 68.1 kDa |
Purity : | >80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Gene Name : | PLK1 polo-like kinase 1 [ Homo sapiens ] |
Official Symbol : | PLK1 |
Synonyms : | PLK1; polo-like kinase 1; PLK, polo like kinase (Drosophila); serine/threonine-protein kinase PLK1; PLK-1; polo like kinase; polo (Drosophia)-like kinase; serine/threonine-protein kinase 13; cell cycle regulated protein kinase; PLK; STPK13; |
Gene ID : | 5347 |
mRNA Refseq : | NM_005030 |
Protein Refseq : | NP_005021 |
MIM : | 602098 |
UniProt ID : | P53350 |
Chromosome Location : | 16p12.2 |
Pathway : | APC/C-mediated degradation of cell cycle proteins, organism-specific biosystem; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1, organism-specific biosystem; Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins, organism-specific biosystem; Cell Cycle, organism-specific biosystem; Cell Cycle, Mitotic, organism-specific biosystem; Cell cycle, organism-specific biosystem; Cell cycle, organism-specific biosystem; |
Function : | ATP binding; anaphase-promoting complex binding; microtubule binding; nucleotide binding; protein binding; protein kinase activity; protein kinase binding; protein serine/threonine kinase activity; protein serine/threonine kinase activity; protein serine/threonine kinase activity; |
Products Types
◆ Recombinant Protein | ||
PLK1-1163H | Recombinant Human PLK1 Protein (D371-S603), His tagged | +Inquiry |
Plk1-4936M | Recombinant Mouse Plk1 Protein, Myc/DDK-tagged | +Inquiry |
PLK1-352H | Recombinant Human PLK1 Protein, MYC/DDK-tagged, C13 and N15-labeled | +Inquiry |
PLK1-1162H | Recombinant Human PLK1 Protein (D371-S603), Tag Free | +Inquiry |
PLK1-4185R | Recombinant Rat PLK1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
PLK1-703HCL | Recombinant Human PLK1 cell lysate | +Inquiry |
PLK1-532MCL | Recombinant Mouse PLK1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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