Recombinant Human COL6A1, MYC/DDK-tagged COL6A1-117H

Recombinant Human COL6A1, MYC/DDK-tagged

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Recombinant Human COL6A1, MYC/DDK-tagged

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Cat.No. : COL6A1-117H
Product Overview : Recombinant Human COL6A1, fused with C-terminal MYC/DDK, was expressed in HEK293 cells.
Description : The collagens are a superfamily of proteins that play a role in maintaining the integrity of various tissues. Collagens are extracellular matrix proteins and have a triple-helical domain as their common structural element. Collagen VI is a major structural component of microfibrils. The basic structural unit of collagen VI is a heterotrimer of the alpha1(VI), alpha2(VI), and alpha3(VI) chains. The alpha2(VI) and alpha3(VI) chains are encoded by the COL6A2 and COL6A3 genes, respectively. The protein encoded by this gene is the alpha 1 subunit of type VI collagen (alpha1(VI) chain). Mutations in the genes that code for the collagen VI subunits result in the autosomal dominant disorder, Bethlem myopathy.
Source : HEK293 cells
Species : Human
Tag : MYC/DDK
Molecular Mass : 106.4 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : COL6A1 collagen, type VI, alpha 1 [ Homo sapiens (human) ]
Official Symbol : COL6A1
Synonyms : collagen, type VI, alpha 1; OPLL; COL6A1; collagen alpha-1(VI) chain; alpha 1 (VI) chain (61 AA); collagen VI, alpha-1 polypeptide; human mRNA for collagen VI alpha-1 C-terminal globular domain9
Gene ID : 1291
mRNA Refseq : NM_001848
Protein Refseq : NP_001839
MIM : 120220
UniProt ID : P12109
Chromosome Location : 21q22.3
Pathway : Assembly of collagen fibrils and other multimeric structures; Collagen biosynthesis and modifying enzymes; ECM-receptor interaction; NCAM1 interactions
Function : platelet-derived growth factor binding

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