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Active Recombinant Mouse Slit3 Protein, His-tagged

Cat.No. : Slit3-123M
Product Overview : Recombinant Mouse Slit3 Protein (Cys34-Val1116), with a C-terminal 6-His tag was expressed in Mouse myeloma cell line.
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  • Gene Information
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Description : Predicted to enable Roundabout binding activity and heparin binding activity. Involved in aortic valve morphogenesis; atrioventricular valve morphogenesis; and ventricular septum morphogenesis. Acts upstream of or within several processes, including axon guidance; negative regulation of cell population proliferation; and negative regulation of gene expression. Located in extracellular space. Is expressed in several structures, including alimentary system; branchial arch; central nervous system; heart; and sensory organ. Used to study congenital diaphragmatic hernia. Orthologous to human SLIT3 (slit guidance ligand 3).
Source : Mouse myeloma cell line
Species : Mouse
Tag : His
Bio-activity : Measured by its ability to enhance neurite outgrowth of E16-E18 rat embryonic cortical neurons. Recombinant Mouse Slit3, immobilized at 2.5-5 μg/mL on a 96-well plate, is able to significantly enhance neurite outgrowth.
Molecular Mass : Predicted Molecular Mass: 122 kDa
SDS-PAGE: 121-153 kDa, reducing conditions
N-terminal Sequence Analysis : Cys34
Endotoxin : < 0.10 EU/μg of the protein by the LAL method.
Purity : > 90% by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
Storage : Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
6 months from date of receipt, -20 to -70 centigrade as supplied.
3 months, -20 to -70 centigrade under sterile conditions after opening.
Storage Buffer : Supplied as a 0.2 μm filtered solution in Sodium Acetate, NaCl and Ethylene Glycol.
Shipping : The product is shipped with dry ice or equivalent.
Gene Name : Slit3 slit guidance ligand 3 [ Mus musculus (house mouse) ]
Official Symbol : Slit3
Synonyms : Slit3; slit guidance ligand 3; Slil2; Slit1; b2b2362.1Clo; slit homolog 3 protein; slit-3
Gene ID : 20564
mRNA Refseq : NM_011412
Protein Refseq : NP_035542
UniProt ID : Q9WVB4

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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