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Recombinant Human FABP3, His-tagged

Cat. No.: FABP3-225H
Product Overview: Recombinant Human FABP3 encoding the human FABP3/HFABP (Val2-Ala133P) with 6 His tag on the N-Terminus was expressed inE.Coli.This protein was purified by Ni-NTA column. MW=17KD.
Description: The intracellular fatty acid-binding proteins (FABPs) belong to a multigene family. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Fatty acid-binding protein 3 gene contains four exons and its function is to arrest growth of mammary epithelial cells. This gene is a candidate tumor suppressor gene for human breast cancer.
Source: E. Coli.
Sequence: Human FABP3/HFABP (Val2-Ala133P)2VDAFLGTWK LVDSKNFDDY MKSLGVGFAT RQVASMTKPT TIIEKNGDIL TLKTHSTFKN TEISFKLGVE FDETTADDRK VKSIVTLDGG KLVHLQKWDG QETTLVRELI DGKLILTLTH GTAVCTRTYE KEA 133.
Purity: >95% in SDS gel.
Formulation: Lyophilized 100μg human FABP3/HFABP in 50 μl of TBS (20 mM Tris, 50mM NaCl, pH8.0). Carry free.
Application: Cell biology, ELISA.
Reconstitution: Add 500 μl deionized water to the vial to prepare a working stock solution at 200μg/mL. Allow to set at least 30 minutes at 4°C, mix well.
Storage: Store lyophilized protein at -20°C or -70°C. Lyophilized protein is stable for up to 6 months from date of receipt at -70°C. Upon reconstitution, this protein can be stored at for a few weeks or at -70°C in a manual defrost freezer for long term storage (six months). Aliquot reconstituted protein to avoid repeated freezing / thawing cycles.
Gene Name: FABP3 fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor) [ Homo sapiens ]
Synonyms: FABP3; fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor); MDGI; FABP11; H-FABP; O-FABP; Fatty acid-binding protein 3, muscle; mammary-derived growth inhibitor; fatty acid binding protein 11
Gene ID: 2170
mRNA Refseq: NM_004102
Protein Refseq: NP_004093
MIM: 134651
UniProt ID: P05413
Chromosome Location: 1p33-p32
Pathway: PPAR signaling pathway
Function: fatty acid binding; icosatetraenoic acid binding; long-chain fatty acid transporter activity; transporter activity

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