Recombinant Human DAPK2

• Cat.No.: DAPK2-26805TH
• Product Overview: Recombinant full length Human DAP Kinase 2 with an N-terminal terminal proprietary tag expressed in a Baculovirus infected Sf9 cell expression system; amino acids 1-370, 67kDa.

Specification

• Description: This gene encodes a protein that belongs to the serine/threonine protein kinase family. This protein contains a N-terminal protein kinase domain followed by a conserved calmodulin-binding domain with significant similarity to that of death-associated protein kinase 1 (DAPK1), a positive regulator of programmed cell death. Overexpression of this gene was shown to induce cell apoptosis.It uses multiple polyadenylation sites.
• Tissue specificity: Ubiquitously expressed in all tissue types examined. High levels in heart, lung and skeletal muscle.
• Biological activity: The Specific activity of DAPK2-26805TH was determined to be 136 nmol/min/mg.
• Form: Liquid
• Storage buffer: Preservative: NoneConstituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, pH 7.5
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequence Similarities: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. DAP kinase subfamily.Contains 1 protein kinase domain.

Gene Information

• Gene Name: DAPK2 death-associated protein kinase 2 [ Homo sapiens ]
• Official Symbol: DAPK2
• Synonyms: DAPK2; death-associated protein kinase 2; DRP 1; MGC119312
• Gene ID: 23604
• mRNA Refseq: NM_014326
• Protein Refseq: NP_055141
• Uniprot ID: Q9UIK4
• Chromosome Location: 15q22.1
• Pathway: Apoptosis, organism-specific biosystem; Bladder cancer, organism-specific biosystem; Bladder cancer, conserved biosystem; Pathways in cancer, organism-specific biosystem; Regulation of Apoptosis, organism-specific biosystem
• Function: ATP binding; calmodulin binding; calmodulin-dependent protein kinase activity; identical protein binding; nucleotide binding