||Recombinant full length human EEF2K with N-terminal proprietary tag expressed in a Baculovirus infected Sf9 cell expression system; amino acids 1-725, 125kDa.
||This gene encodes a highly conserved protein kinase in the calmodulin-mediated signaling pathway that links activation of cell surface receptors to cell division. This kinase is involved in the regulation of protein synthesis. It phosphorylates eukaryotic elongation factor 2 (EEF2) and thus inhibits the EEF2 function. The activity of this kinase is increased in many cancers and may be a valid target for anti-cancer treatment.
||Specific activity of EEF2K was determined to be 50nmol/min/mg as per activity assay protocol
||Preservative: NoneConstituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, pH 7.5
||Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
||Belongs to the protein kinase superfamily. Alpha-type protein kinase family.Contains 1 alpha-type protein kinase domain.