Recombinant Human NEK7

• Cat.No.: NEK7-28259TH
• Product Overview: Recombinant full length NEK7 protein (Human), was expressed by baculovirus in Sf9 insect cells using a N-terminal tag, MW 63kDa.

Specification

• Description: NIMA-related kinases share high amino acid sequence identity with the gene product of the Aspergillus nidulans never in mitosis A gene, which controls initiation of mitosis.
• Tissue specificity: Highly expressed in lung, muscle, testis, brain, heart, liver, leukocyte and spleen. Lower expression in ovary, prostate and kidney. No expression seen in small intestine.
• Form: Liquid
• Purity: >90% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, pH 7.5
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequence Similarities: Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.Contains 1 protein kinase domain.

Gene Information

• Gene Name: NEK7 NIMA (never in mitosis gene a)-related kinase 7 [ Homo sapiens ]
• Official Symbol: NEK7
• Synonyms: NEK7; NIMA (never in mitosis gene a)-related kinase 7; serine/threonine-protein kinase Nek7
• Gene ID: 140609
• mRNA Refseq: NM_133494
• Protein Refseq: NP_598001
• MIM: 606848
• Uniprot ID: Q8TDX7
• Chromosome Location: 1q31.3
• Function: ATP binding; metal ion binding; nucleotide binding; protein serine/threonine kinase activity