Recombinant Human PDK4, His-tagged
Cat.No. : | PDK4-653H |
Product Overview : | Recombinant Human PDK4 with a His tag is expressed inBacteriaand column-purified. |
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- Gene Information
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Cat. No. : | PDK4-653H |
Description : | PDH kinases (PDK"s) deactivate PDH by reversible phosphorylation. In humans and rodents, 4 PDK"s are present in an organ-dependent manner. In all cases, PDK"s are physically part of the PDH complex (binding via lipoyl domain 2 of E2), and they phosphorylate the E1 subunit at 3 specific serine residues. PDH phosphatases remove the phosphorylation and restore activity of PDH. |
Source : | Bacteria. |
Storage : | Store at -80°C. |
Gene Name : | PDK4 pyruvate dehydrogenase kinase, isozyme 4 [ Homo sapiens ] |
Synonyms : | PDK4; pyruvate dehydrogenase kinase, isozyme 4; [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4, mitochondrial; pyruvate dehydrogenase kinase, isoenzyme 4; pyruvate dehydrogenase, lipoamide, kinase isozyme 4, mitochondrial; EC 2.7.11.2; FLJ40832 |
Gene ID : | 5166 |
mRNA Refseq : | NM_002612 |
Protein Refseq : | NP_002603 |
MIM : | 602527 |
UniProt ID : | Q16654 |
Chromosome Location : | 7q21.3 |
Pathway : | Integration of energy metabolism; Pyruvate metabolism and Citric Acid (TCA) cycle |
Function : | ATP binding; nucleotide binding; protein heterodimerization activity; pyruvate dehydrogenase (acetyl-transferring) kinase activity; protein homodimerization activity; transferase activity; two-component sensor activity |
Products Types
◆ Recombinant Protein | ||
PDK4-823H | Recombinant Human PDK4 Protein, MYC/DDK-tagged | +Inquiry |
PDK4-0621H | Recombinant Human PDK4 Protein (M1-M411), Tag Free | +Inquiry |
PDK4-4010R | Recombinant Rat PDK4 Protein, His (Fc)-Avi-tagged | +Inquiry |
Pdk4-4769M | Recombinant Mouse Pdk4 Protein, Myc/DDK-tagged | +Inquiry |
PDK4-0622H | Recombinant Human PDK4 Protein (M1-M411), GST tagged | +Inquiry |
◆ Lysates | ||
PDK4-001MCL | Recombinant Mouse PDK4 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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