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Recombinant Human PDK4, His-tagged

Cat.No. : PDK4-653H
Product Overview : Recombinant Human PDK4 with a His tag is expressed inBacteriaand column-purified.
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  • Gene Information
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Cat. No. : PDK4-653H
Description : PDH kinases (PDK"s) deactivate PDH by reversible phosphorylation. In humans and rodents, 4 PDK"s are present in an organ-dependent manner. In all cases, PDK"s are physically part of the PDH complex (binding via lipoyl domain 2 of E2), and they phosphorylate the E1 subunit at 3 specific serine residues. PDH phosphatases remove the phosphorylation and restore activity of PDH.
Source : Bacteria.
Storage : Store at -80°C.
Gene Name : PDK4 pyruvate dehydrogenase kinase, isozyme 4 [ Homo sapiens ]
Synonyms : PDK4; pyruvate dehydrogenase kinase, isozyme 4; [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4, mitochondrial; pyruvate dehydrogenase kinase, isoenzyme 4; pyruvate dehydrogenase, lipoamide, kinase isozyme 4, mitochondrial; EC 2.7.11.2; FLJ40832
Gene ID : 5166
mRNA Refseq : NM_002612
Protein Refseq : NP_002603
MIM : 602527
UniProt ID : Q16654
Chromosome Location : 7q21.3
Pathway : Integration of energy metabolism; Pyruvate metabolism and Citric Acid (TCA) cycle
Function : ATP binding; nucleotide binding; protein heterodimerization activity; pyruvate dehydrogenase (acetyl-transferring) kinase activity; protein homodimerization activity; transferase activity; two-component sensor activity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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