Recombinant Human EPH Receptor A7, GST-His EPHA7-745H

Recombinant Human EPH Receptor A7, GST-His

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Recombinant Human EPH Receptor A7, GST-His

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Cat. No. : EPHA7-745H
Product Overview : Recombinant Human EPHA7, C-terminal fragment, amino acids G579-V998, activated, N-terminal GSTHIS6 fusion protein with a Thrombin and a 3C cleavage site, expressed inSf9insect cells. MW = 78,443 Da.
Description : EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.
Source : Baculovirus infected Sf9 cells.
Purification : GST-Affinity Chromatography.
Activation : in vitro autoactivation.
Product Identity : EPHA7 was confirmed as EPHA7 by mass spectroscopy LC-ESI-MS/MS.
Storage Buffer : 50 mM HEPES pH 7.5, 100 mM NaCl, 5 mM DTT, 15 mM reduced glutathione, 20% glycerol.
Concentration : 0.317 μg/μl (Bradford method using BSA [Sigma, cat# A-7638, Lot 79H7641] as standard protein).
Specific Activity : 21 pmol/μg×min.
Storage : -80°C. Avoid repeated freeze-thaw cycles!
Gene Name : EPHA7 EPH receptor A7 [ Homo sapiens ]
Synonyms : EPHA7; EPH receptor A7; EHK3; HEK11; ephrin type-A receptor 7; EK11; EHK-3; EPH-like kinase 11; EPH homology kinase 3; Eph homology kinase-3; receptor protein-tyrosine kinase HEK11; tyrosine-protein kinase receptor EHK-3; EC 2.7.10.1
Gene ID : 2045
mRNA Refseq : NM_004440
Protein Refseq : NP_004431
MIM : 602190
UniProt ID : Q15375
Chromosome Location : 6q16.1
Pathway : Axon guidance
Function : ATP binding; chemorepellent activity; ephrin receptor activity; ephrin receptor binding; nucleotide binding; protein binding; protein tyrosine kinase activity; receptor activity; transferase activity; transmembrane receptor protein tyrosine kinase activity

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