Recombinant Human Serum/Glucocorticoid Regulated Kinase 2
Cat.No. : | SGK2-659H |
- Specification
- Gene Information
- Related Products
Cat. No. : | SGK2-659H |
Description : | SGK2 is a member of the serum- and glucocorticoid-induced kinases (SGK) which are serine-threonine kinases and belong to the "AGC" kinase subfamily, which includes protein kinases A, G, and C, and its catalytic domain is most similar to protein kinase B (PKB). SGK2, like the other two isoforms SGK1 and SGK3, is stimulated by insulin and insulin-like growth factor-1 (IGF-1), and has been shown to enhance Na(+)/K(+)-ATPase activity in a variety of cells. |
Source : | E.coli. |
Application : | Kinase activity is measured as the molar amount of phosphate incorporated into the Akt/SGK substrate peptide (RPRAATF), per minute per mg protein at 30 °C using a final concentration of 50 μM [32P] ATP. |
Biochem/physiol Actions : | SGK2 is a member of the serum- and glucocorticoid-induced kinases (SGK) which are serine-threonine kinases and belong to the "AGC" kinase subfamily, which includes protein kinases A, G, and C and has SGK2 enhances Na+/K+-ATPase activity in a variety of cells. In addition, SGK2 mimics the function of SGK1 and SGK3 and participates in the regulation of renal epithelial Na+ channel ENaC activity. |
Physical Form : | Supplied at 50 μL in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.25 mM dithiothreitol (DTT), 0.1 mM EGTA, and 30% glycerol. |
Assay : | ≥75% (SDS-PAGE). |
Form : | aqueous glycerol solution. |
Mol Wt : | protein apparent mol wt ~66 kDa. |
Storage Temp : | −70°C. |
Gene Name : | SGK2 serum/glucocorticoid regulated kinase 2 [ Homo sapiens ] |
Synonyms : | SGK2; serum/glucocorticoid regulated kinase 2; H-SGK2; dJ138B7.2; OTTHUMP00000031705; EC 2.7.11.1; OTTHUMP00000031702; OTTHUMP00000031703; Serum/glucocorticoid-regulated kinase 2; Serine/threonine-protein kinase Sgk2 |
Gene ID : | 10110 |
mRNA Refseq : | NM_016276 |
Protein Refseq : | NP_057360 |
MIM : | 607589 |
UniProt ID : | Q9HBY8 |
Chromosome Location : | 20q13.2 |
Function : | ATP binding; nucleotide binding; potassium channel regulator activity; protein serine/threonine kinase activity; sodium channel regulator activity; transferase activity |
Products Types
◆ Recombinant Protein | ||
SGK2-1182H | Recombinant Human SGK2 Protein (Q2-C427), Tag Free | +Inquiry |
Sgk2-5825M | Recombinant Mouse Sgk2 Protein, Myc/DDK-tagged | +Inquiry |
SGK2-1183H | Recombinant Human SGK2 Protein (Q2-C427), GST tagged | +Inquiry |
SGK2-5024R | Recombinant Rat SGK2 Protein, His (Fc)-Avi-tagged | +Inquiry |
SGK2-429H | Recombinant Human SGK2, GST-tagged, Active | +Inquiry |
◆ Lysates | ||
SGK2-1885HCL | Recombinant Human SGK2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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